VIM and RAB8B

Number of citations of the paper that reports this interaction (PMID 12639940)
17

Data Source:
HPRD (in vivo)

		VIM	RAB8B
Gene Name		vimentin	RAB8B, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome	Mitochondrion Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Phagocytic Vesicle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein C-terminus Binding Identical Protein Binding Scaffold Protein Binding	GTPase Activity Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Positive Regulation Of Gene Expression Negative Regulation Of Neuron Projection Development Astrocyte Development Viral Process Muscle Filament Sliding Intermediate Filament Organization Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development	Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Adherens Junction Organization Cilium Assembly Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Protein Localization To Plasma Membrane
Pathways		Apoptotic cleavage of cellular proteins Striated Muscle Contraction Programmed Cell Death Apoptotic execution phase Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		140 interactors: ABLIM1 AKT1 ALS2CR11 ANKRD35 ANXA7 APIP APLP1 APP ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CDH5 CDK1 CDKN1A CHD3 COPS6 CRCT1 CREB1 CRMP1 CWF19L2 DCTN1 DEFB1 DGCR14 DIS3L2 DNM1L DPPA4 DSP DYNLL1 EIF3I FABP4 FAM107A FAM118B FUBP1 GADD45A GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HTRA2 ING5 ITGB4 IVNS1ABP KARS KAT7 KIAA0408 KIAA1377 KIF15 KRT20 LOR LRIF1 MAFG MAN2A2 MEN1 MICAL1 MRPL44 NEFL NFATC2 NIF3L1 NME2 NOC4L NR1H2 NUP85 OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PRKACA PRPH PSMA1 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SDCCAG3 SERBP1 SETDB1 SH3GL1 SH3GL3 SH3YL1 SIRT6 SLC25A6 SLC27A6 SMAD3 SRRT STX1A SUMO2 SUMO3 SYN1 TAB2 TCHP TNFRSF14 TNNT1 TRIM28 TRIM29 TRIOBP TSC22D1 TTR TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1D1 YWHAE YWHAZ ZHX1 ZNF384	7 interactors: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM
Entrez ID		7431	51762
HPRD ID		01899	11476
Ensembl ID		ENSG00000026025	ENSG00000166128
Uniprot IDs		P08670	F5GY21 Q92930
PDB IDs		1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1
Enriched GO Terms of Interacting Partners?		Programmed Cell Death Apoptotic Process Cell Death Death Execution Phase Of Apoptosis Regulation Of Cell Death Response To Abiotic Stimulus Regulation Of Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Stress Positive Regulation Of Proteolysis Regulation Of Cellular Localization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Cellular Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Cell Death Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization Organelle Organization Cell Cycle Process Cellular Response To Stress Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Gene Expression Immune System Process Regulation Of Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Anatomical Structure Development Positive Regulation Of Signal Transduction Mitotic Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Programmed Cell Death Cellular Process Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Viral Process Intrinsic Apoptotic Signaling Pathway	Cellular Localization Organelle Organization Lens Fiber Cell Differentiation Cellular Component Assembly Establishment Of Localization In Cell Exocytosis Cell Cycle Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cytoskeleton Organization Platelet Degranulation Cell Division Execution Phase Of Apoptosis Synapse Assembly Cell Cycle Secretion By Cell Lens Development In Camera-type Eye Protein Polymerization Vesicle-mediated Transport Regulation Of Body Fluid Levels G2/M Transition Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Secretion Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Process Regulation Of Neurogenesis Collateral Sprouting In Absence Of Injury Mitotic Cell Cycle Microtubule-based Process Synapse Organization Membrane Raft Localization Negative Regulation Of Neuron Differentiation Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Indole-3-methanol Regulation Of Cell Development Membrane Organization Epithelial Cell Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Activation Of Anaphase-promoting Complex Activity Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Apoptotic Process Central Nervous System Development Bergmann Glial Cell Differentiation Salivary Gland Cavitation Programmed Cell Death Mitotic Cell Cycle Phase Transition Protein Complex Assembly Cell Cycle Phase Transition
Tagcloud ?		10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z	1a 1b adaptor addiction ap2 ca1 cation channels cyclic electrophysiology gated hcn hcn1 hcn2 hippocampal hyperpolarization imbalance learning ltp maze morphine mu2 neurological pka potentiation sc tpr trip8b vital
Tagcloud (Difference) ?		10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z	1a 1b adaptor addiction ap2 ca1 cation channels cyclic electrophysiology gated hcn hcn1 hcn2 hippocampal hyperpolarization imbalance learning ltp maze morphine mu2 neurological pka potentiation sc tpr trip8b vital
Tagcloud (Intersection) ?