VIM and GFAP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VIM	GFAP
Gene Name		vimentin	glial fibrillary acidic protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome	Cytoplasm Cytosol Intermediate Filament Membrane Cell Body Astrocyte End-foot
	Molecular Function	Glycoprotein Binding Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein C-terminus Binding Identical Protein Binding Scaffold Protein Binding	Integrin Binding Structural Constituent Of Cytoskeleton Kinase Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Positive Regulation Of Gene Expression Negative Regulation Of Neuron Projection Development Astrocyte Development Viral Process Muscle Filament Sliding Intermediate Filament Organization Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development	Response To Wounding Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Neuron Projection Development Astrocyte Development Extracellular Matrix Organization Neuron Projection Regeneration Intermediate Filament Organization Regulation Of Neurotransmitter Uptake Bergmann Glial Cell Differentiation Long-term Synaptic Potentiation
Pathways		Apoptotic cleavage of cellular proteins Striated Muscle Contraction Programmed Cell Death Apoptotic execution phase Caspase-mediated cleavage of cytoskeletal proteins	Nuclear signaling by ERBB4 Signaling by ERBB4
Drugs
Diseases
GWAS
Protein-Protein Interactions		140 interactors: ABLIM1 AKT1 ALS2CR11 ANKRD35 ANXA7 APIP APLP1 APP ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CDH5 CDK1 CDKN1A CHD3 COPS6 CRCT1 CREB1 CRMP1 CWF19L2 DCTN1 DEFB1 DGCR14 DIS3L2 DNM1L DPPA4 DSP DYNLL1 EIF3I FABP4 FAM107A FAM118B FUBP1 GADD45A GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HTRA2 ING5 ITGB4 IVNS1ABP KARS KAT7 KIAA0408 KIAA1377 KIF15 KRT20 LOR LRIF1 MAFG MAN2A2 MEN1 MICAL1 MRPL44 NEFL NFATC2 NIF3L1 NME2 NOC4L NR1H2 NUP85 OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PRKACA PRPH PSMA1 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SDCCAG3 SERBP1 SETDB1 SH3GL1 SH3GL3 SH3YL1 SIRT6 SLC25A6 SLC27A6 SMAD3 SRRT STX1A SUMO2 SUMO3 SYN1 TAB2 TCHP TNFRSF14 TNNT1 TRIM28 TRIM29 TRIOBP TSC22D1 TTR TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1D1 YWHAE YWHAZ ZHX1 ZNF384	46 interactors: AES APP AURKB BIRC2 C6orf165 CAMK2A CDK1 CEP76 CRYAB FAM50B GOLGA2 GRAP2 HGS IKBKG KIAA0408 KRT13 KRT15 LGALS14 LMO2 MEN1 MOS MYO15B NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SRC STAT1 TRIM27 TUBGCP4 VIM ZC2HC1C
Entrez ID		7431	2670
HPRD ID		01899	00675
Ensembl ID		ENSG00000026025	ENSG00000131095
Uniprot IDs		P08670	A7REI1 P14136
PDB IDs		1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1
Enriched GO Terms of Interacting Partners?		Programmed Cell Death Apoptotic Process Cell Death Death Execution Phase Of Apoptosis Regulation Of Cell Death Response To Abiotic Stimulus Regulation Of Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Stress Positive Regulation Of Proteolysis Regulation Of Cellular Localization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Cellular Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Cell Death Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization Organelle Organization Cell Cycle Process Cellular Response To Stress Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Gene Expression Immune System Process Regulation Of Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Anatomical Structure Development Positive Regulation Of Signal Transduction Mitotic Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Programmed Cell Death Cellular Process Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Viral Process Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Regulation Of Protein Binding Programmed Cell Death Cell Death Death Regulation Of Apoptotic Process Response To Abiotic Stimulus Immune Response Regulation Of Cell Death Regulation Of Binding Immune System Process Innate Immune Response Regulation Of Cellular Component Organization Cellular Response To Stimulus Regulation Of Cell Differentiation Negative Regulation Of Apoptotic Process Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Regulation Of Signaling Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Peptidyl-serine Phosphorylation Negative Regulation Of Cell Death Regulation Of Kinase Activity Protein Autophosphorylation Negative Regulation Of Cellular Protein Metabolic Process Signal Transduction Response To Stimulus Regulation Of Immune System Process Negative Regulation Of Signal Transduction Negative Regulation Of Protein Metabolic Process Defense Response Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Signaling Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cell Communication Mitotic Nuclear Envelope Disassembly Response To Hypoxia Histone Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Signal Transduction Negative Regulation Of Cellular Metabolic Process Response To Stress Vascular Endothelial Growth Factor Receptor Signaling Pathway Nuclear Envelope Disassembly
Tagcloud ?		10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z	astrocyte astroglia bioactivation catechols dense diaminobenzidine effete elemental faint fourfold gliosomes heterogeneously histochemical inclusions laden microanalytical microprobe minority nigra nigral parkinsonism peaks peroxidase predisposing senescent sequestration subcortical substantia ultrastructural
Tagcloud (Difference) ?		10p13 17q21 5q15 6p24 australian british cl cleft crtl1 d1s58 d1s65 der excluded f13a1 flank inheritance linkage lip lod multipoint palate rara syndromic theta unrelated van vws woude z	astrocyte astroglia bioactivation catechols dense diaminobenzidine effete elemental faint fourfold gliosomes heterogeneously histochemical inclusions laden microanalytical microprobe minority nigra nigral parkinsonism peaks peroxidase predisposing senescent sequestration subcortical substantia ultrastructural
Tagcloud (Intersection) ?