S100P and GH2

Number of citations of the paper that reports this interaction (PubMedID 36233301)
61

Data Source:
BioGRID (pull down)

		S100P	GH2
Description		S100 calcium binding protein P	growth hormone 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome	Extracellular Region Extracellular Space Cytoplasm Endomembrane System Endosome Lumen Vesicle
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Growth Hormone Receptor Binding Hormone Activity Growth Factor Activity
	Biological Process	Endothelial Cell Migration	Response To Nutrient Levels Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Animal Organ Development Growth Hormone Receptor Signaling Pathway
Pathways		Neutrophil degranulation	Prolactin receptor signaling Prolactin receptor signaling Growth hormone receptor signaling Growth hormone receptor signaling
Drugs		Cromoglicic acid
Diseases
GWAS		Obesity-related traits ( 23251661)	Height ( 31562340 33713608) Prudent dietary pattern ( 28644415) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A	3 interacting genes: GHR S100A6 S100P
Entrez ID		6286	2689
HPRD ID		02792	00750
Ensembl ID		ENSG00000163993	ENSG00000136487
Uniprot IDs		P25815	A0A0M6L0J9 P01242
PDB IDs		1J55 1OZO 2MJW 7NMI
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	Protein Homodimerization Activity Calcium-dependent Protein Binding Growth Hormone Receptor Activity Growth Hormone Receptor Complex Response To Growth Hormone Response To Cycloheximide Regulation Of Growth Hormone Receptor Signaling Pathway Response To Gravity Growth Hormone Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Growth Hormone Receptor Signaling Pathway Extracellular Region Taurine Metabolic Process Identical Protein Binding Monoatomic Ion Transmembrane Transporter Activity Tropomyosin Binding S100 Protein Binding Protein Tyrosine Kinase Activator Activity Proline-rich Region Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Calcium Ion Binding Transition Metal Ion Binding Growth Hormone Receptor Signaling Pathway Microvillus Membrane Response To Food Regulation Of Response To Nutrient Levels Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT SH2 Domain Binding Peptide Hormone Binding Protein Tyrosine Kinase Binding Cytokine Binding Growth Factor Binding Positive Regulation Of Receptor Signaling Pathway Via STAT Positive Regulation Of Cell Population Proliferation Cytokine Receptor Activity Positive Regulation Of Fibroblast Proliferation
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