S100P and S100A2

Number of citations of the paper that reports this interaction (PubMedID 15171681)
44

Data Source:
HPRD (two hybrid, in vitro)

		S100P	S100A2
Description		S100 calcium binding protein P	S100 calcium binding protein A2
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Endothelial Cell Migration	Endothelial Cell Migration
Pathways		Neutrophil degranulation
Drugs		Cromoglicic acid	Olopatadine Calcium Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A	16 interacting genes: ARL13B CEP20 EPO FAM209A FKBP4 MDM2 PPID S100A1 S100A3 S100B S100P STUB1 TP53 TPM1 TPM2 TPM3
Entrez ID		6286	6273
HPRD ID		02792	01508
Ensembl ID		ENSG00000163993	ENSG00000196754
Uniprot IDs		P25815	P29034 Q5RHS7 R4GN49
PDB IDs		1J55 1OZO 2MJW 7NMI	2RGI 4DUQ
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	Muscle Thin Filament Tropomyosin Calcium-dependent Protein Binding Cellular Response To Actinomycin D Response To Hypoxia Response To Decreased Oxygen Levels Tau Protein Binding Response To Actinomycin D Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Cellular Response To UV-C Response To Oxygen Levels Cellular Response To Oxygen Levels Heat Shock Protein Binding Protein Homodimerization Activity Cellular Response To Antibiotic Regulation Of Blood Circulation Cellular Response To UV Response To UV-C Identical Protein Binding S100 Protein Binding Actin Filament Regulation Of System Process Response To Salt Stress Cellular Response To Light Stimulus Transition Metal Ion Binding Cytoplasm System Process Cytoskeleton Disordered Domain Specific Binding Cellular Response To Gamma Radiation Response To UV Cytosol Regulation Of ATP-dependent Activity Peptidyl-prolyl Cis-trans Isomerase Activity Cellular Response To Radiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Embryo Implantation Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Erythrocyte Apoptotic Process Steroid Hormone Receptor Complex Assembly Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Heart Contraction DNA Damage Response, Signal Transduction By P53 Class Mediator Supramolecular Fiber Organization Hsp90 Protein Binding Hsp70 Protein Binding Regulation Of Mitophagy
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