S100P and CLCF1

Number of citations of the paper that reports this interaction (PubMedID 34933172)
0

Data Source:
BioGRID (pull down)

		S100P	CLCF1
Description		S100 calcium binding protein P	cardiotrophin like cytokine factor 1
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome	Extracellular Region Extracellular Space CRLF-CLCF1 Complex CNTFR-CLCF1 Complex
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Signaling Receptor Binding Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Protein Binding Growth Factor Activity Receptor Ligand Activity
	Biological Process	Endothelial Cell Migration	Positive Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of B Cell Proliferation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Isotype Switching To IgE Isotypes Positive Regulation Of Astrocyte Differentiation Cell Surface Receptor Signaling Pathway Via STAT
Pathways		Neutrophil degranulation	IL-6-type cytokine receptor ligand interactions
Drugs		Cromoglicic acid
Diseases			Cold-induced sweating syndrome (CISS) and Crisponi syndrome (CRISPS)
GWAS		Obesity-related traits ( 23251661)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A	5 interacting genes: CNTFR CRLF1 S100A1 S100A6 S100P
Entrez ID		6286	23529
HPRD ID		02792	09643
Ensembl ID		ENSG00000163993	ENSG00000175505
Uniprot IDs		P25815	Q9UBD9
PDB IDs		1J55 1OZO 2MJW 7NMI	8D7H 8D7R
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	Negative Regulation Of Motor Neuron Apoptotic Process Positive Regulation Of Cell Population Proliferation Calcium-dependent Protein Binding Regulation Of Motor Neuron Apoptotic Process S100 Protein Binding Cytokine Binding Regulation Of Cell Population Proliferation Cytokine Receptor Activity Cytokine-mediated Signaling Pathway Interleukin-11 Receptor Activity Negative Regulation Of Neuron Apoptotic Process CNTFR-CLCF1 Complex Ciliary Neurotrophic Factor Receptor Activity Ciliary Neurotrophic Factor-mediated Signaling Pathway Ciliary Neurotrophic Factor Receptor Complex Interleukin-11 Binding Regulation Of Oligodendrocyte Progenitor Proliferation Platelet Degranulation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Histamine Secretion By Mast Cell Negative Regulation Of Mast Cell Proliferation Fc Receptor Mediated Inhibitory Signaling Pathway Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Eosinophil Differentiation Glycosphingolipid Binding Postsynaptic Specialization, Intracellular Component Cytoplasmic Side Of Plasma Membrane SH3 Domain Binding Positive Regulation Of Mast Cell Proliferation Integrin Alpha2-beta1 Complex Tolerance Induction To Self Antigen Interleukin-5-mediated Signaling Pathway Positive Regulation Of Oligodendrocyte Progenitor Proliferation Positive Regulation Of Dendritic Cell Apoptotic Process Protein Homodimerization Activity Calcium Ion Binding Ciliary Neurotrophic Factor Receptor Binding CRLF-CLCF1 Complex Synaptic Receptor Adaptor Activity Interleukin-11-mediated Signaling Pathway Phosphatidylinositol 3-kinase Activator Activity C-X-C Chemokine Receptor CXCR4 Signaling Pathway Histamine Secretion Brainstem Development Mitochondrial Crista Regulation Of Mast Cell Proliferation Signaling Receptor Activator Activity Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Histamine Transport Suckling Behavior
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