S100P and ARC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		S100P	ARC
Description		S100 calcium binding protein P	activity regulated cytoskeleton associated protein
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome	Acrosomal Vesicle Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Cell Projection Neuronal Cell Body Dendritic Spine Membrane Raft Synapse Postsynaptic Membrane Neuronal Ribonucleoprotein Granule Glutamatergic Synapse Virus-like Capsid Extracellular Vesicle
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Endothelial Cell Migration	Endocytosis Cytoskeleton Organization Endoderm Development Long-term Memory Anterior/posterior Pattern Specification Cell Migration Regulation Of Cell Morphogenesis Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission MRNA Transport Protein Homooligomerization Long-term Synaptic Potentiation Dendritic Spine Morphogenesis Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Intercellular Transport Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Synaptic Depression
Pathways		Neutrophil degranulation	NGF-stimulated transcription NGF-stimulated transcription
Drugs		Cromoglicic acid
Diseases
GWAS		Obesity-related traits ( 23251661)	Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Automobile speeding propensity ( 30643258)
Interacting Genes		46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A	7 interacting genes: CSRP2 KRT15 S100P SH2D4A SPTBN4 TBX18 UBE3A
Entrez ID		6286	23237
HPRD ID		02792	12469
Ensembl ID		ENSG00000163993	ENSG00000198576
Uniprot IDs		P25815	Q7LC44
PDB IDs		1J55 1OZO 2MJW 7NMI	6TN7 6TNQ 6TQ0 6YTU 7R1Z 7R23 8QF4 8QF5
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	Sperm Entry Positive Regulation Of Golgi Lumen Acidification Sinoatrial Node Cell Fate Commitment Phosphatase Binding Muscle Tissue Development Tissue Development Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Cellular PH Reduction Regulation Of Golgi Lumen Acidification Ureter Development RNA Polymerase II Transcription Repressor Complex Sinoatrial Node Cell Development Neural Plate Pattern Specification Sinoatrial Node Development Cardiac Muscle Cell Fate Commitment Regulation Of SA Node Cell Action Potential Neural Plate Anterior/posterior Regionalization Cytoskeletal Protein-membrane Anchor Activity Clustering Of Voltage-gated Sodium Channels Axon Hillock Cell Body Fiber Paranode Region Of Axon Spectrin
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