S100P and S100A1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro, two hybrid)

		S100P	S100A1
Gene Name		S100 calcium binding protein P	S100 calcium binding protein A1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microvillus Membrane Extracellular Vesicular Exosome	Nucleus Sarcoplasmic Reticulum Z Disc M Band Neuron Projection Protein Complex
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Response To Organic Substance Endothelial Cell Migration	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity
Pathways
Drugs		Cromoglicic acid	Olopatadine
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: AGER CACYBP EZR S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11	24 interactors: ACTA1 AGER ANXA6 ATP2A2 CACYBP CAPZA1 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		6286	6271
HPRD ID		02792	01489
Ensembl ID			ENSG00000160678
Uniprot IDs		P25815	P23297
PDB IDs		1J55 1OZO	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spliceosomal Complex Disassembly Negative Regulation Of DNA Recombination At Telomere System Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Chaperone-mediated Protein Complex Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Skeletal Muscle Cell Differentiation Multicellular Organismal Development Membrane To Membrane Docking Protection From Non-homologous End Joining At Telomere Anatomical Structure Development Regulation Of Cell Shape Telomere Capping Protein Localization To Chromosome, Telomeric Region Ubiquitin-dependent SMAD Protein Catabolic Process Cell Morphogenesis Involved In Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Response To Methylmercury Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance	Muscle System Process Response To Abiotic Stimulus Regulation Of Cardiac Muscle Cell Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Protein Complex Assembly Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Striated Muscle Contraction Glycogen Catabolic Process Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Polysaccharide Catabolic Process Calcium Ion Transport Relaxation Of Muscle Striated Muscle Tissue Development Negative Regulation Of Heart Contraction Skeletal Muscle Fiber Development Response To Hormone Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Metal Ion Muscle Tissue Development Cellular Component Assembly Myotube Cell Development Regulation Of Cellular Localization Cellular Carbohydrate Catabolic Process Regulation Of The Force Of Heart Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Response To Wounding Regulation Of Ion Homeostasis Regulation Of Actin Filament-based Process Cellular Metal Ion Homeostasis Cellular Response To Alkaloid Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Astrocyte Differentiation Cytosolic Calcium Ion Homeostasis Cellular Cation Homeostasis Actin-mediated Cell Contraction Cellular Ion Homeostasis Response To Peptide Hormone Cardiac Conduction Tissue Development Negative Regulation Of Striated Muscle Tissue Development Steroid Hormone Receptor Complex Assembly Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Positive Regulation Of Schwann Cell Proliferation
Tagcloud ?		adenoma bda bdas bile columnar cuboidal duct ductular ema glut imp indexes interlobular lumen meyenburg morphologic muc1 muc6 narrow ncam nodular peribiliary resembling sclerotic sized stroma uniform vmc von	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Difference) ?		adenoma bda bdas bile columnar cuboidal duct ductular ema glut imp indexes interlobular lumen meyenburg morphologic muc1 muc6 narrow ncam nodular peribiliary resembling sclerotic sized stroma uniform vmc von	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Intersection) ?