S100P and IL3

Number of citations of the paper that reports this interaction (PubMedID 36233301)
61

Data Source:
BioGRID (pull down)

		S100P	IL3
Description		S100 calcium binding protein P	interleukin 3
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Cytokine Activity Interleukin-3 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Endothelial Cell Migration	Immune Response Cell-cell Signaling Nervous System Development Positive Regulation Of Cell Population Proliferation Embryonic Hemopoiesis Interleukin-3-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Via STAT
Pathways		Neutrophil degranulation	Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade RUNX1 regulates transcription of genes involved in interleukin signaling Interleukin receptor SHC signaling
Drugs		Cromoglicic acid	Amlexanox Zinc Polaprezinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Obesity-related traits ( 23251661)	Body mass index ( 28552196) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 21102463 22412388 28067908) Inflammatory bowel disease ( 23128233 28067908) Perceived unattractiveness to mosquitoes ( 28199695) Rheumatoid arthritis ( 24390342 30423114) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A	7 interacting genes: CSF2RB HRAS IL3RA PIK3CA PIK3CD S100A6 S100P
Entrez ID		6286	3562
HPRD ID		02792	00987
Ensembl ID		ENSG00000163993	ENSG00000164399
Uniprot IDs		P25815	P08700
PDB IDs		1J55 1OZO 2MJW 7NMI	1JLI 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	Interleukin-3 Receptor Activity Regulation Of Cell Population Proliferation Interleukin-3-mediated Signaling Pathway Cellular Response To Interleukin-3 1-phosphatidylinositol-4-phosphate 3-kinase Activity 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Phosphatidylinositol 3-kinase Complex Positive Regulation Of Cell Population Proliferation Phosphatidylinositol 3-kinase Complex, Class IA 1-phosphatidylinositol-3-kinase Activity Signal Transduction T Cell Receptor Signaling Pathway Vascular Endothelial Growth Factor Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling Cell Surface Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Protein Refolding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death ATP-dependent Protein Folding Chaperone Regulation Of Immune Response Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Component Biogenesis Regulation Of Immune System Process Regulation Of Cytoskeleton Organization Cytokine Receptor Activity Adipose Tissue Development Regulation Of Cell Cycle Regulation Of Erythrocyte Differentiation Plasma Membrane Immune Response-activating Cell Surface Receptor Signaling Pathway Phosphatidylinositol Phosphate Biosynthetic Process Positive Regulation Of Fibroblast Proliferation RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Protein Folding Chaperone Immune System Process Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Heat Shock Protein Binding Regulation Of Microtubule Polymerization Adaptive Immune Response Perinuclear Region Of Cytoplasm Connective Tissue Development Interleukin-5 Receptor Activity Insulin Receptor Signaling Pathway GTPase Complex Denatured Protein Binding RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?