DNMBP and NCKAP1

Number of citations of the paper that reports this interaction (PMID 14506234)
39

Data Source:
HPRD (in vitro)

		DNMBP	NCKAP1
Gene Name		dynamin binding protein	NCK-associated protein 1
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Gene Ontology Annotations	Cellular Component	Golgi Stack Cytoskeleton Cell Junction Synapse	Cytosol Focal Adhesion Integral Component Of Membrane SCAR Complex Lamellipodium Membrane Extracellular Vesicular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Protein Complex Binding Rac GTPase Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction	In Utero Embryonic Development Somitogenesis Neural Tube Closure Apoptotic Process Zygotic Determination Of Anterior/posterior Axis, Embryo Central Nervous System Development Endoderm Development Mesodermal Cell Migration Embryonic Body Morphogenesis Positive Regulation Of Lamellipodium Assembly Rac Protein Signal Transduction Lamellipodium Assembly Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Protein Localization Embryonic Heart Tube Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cell Migration Involved In Gastrulation Innate Immune Response Basal Protein Localization Apical Protein Localization Vascular Endothelial Growth Factor Receptor Signaling Pathway Paraxial Mesoderm Morphogenesis Notochord Morphogenesis Embryonic Foregut Morphogenesis Protein Stabilization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ACTA1 ARHGAP17 BIN3 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2	11 interactors: ABI1 BRK1 CYFIP2 DNMBP GAS7 NCK1 RAC1 SPP1 WASF1 WASF2 YWHAG
Entrez ID		23268	10787
HPRD ID		10918	05353
Ensembl ID		ENSG00000107554	ENSG00000061676
Uniprot IDs		Q6XZF7	Q9Y2A7
PDB IDs		1UG1 1UHC 4GLM	3P8C
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Cytoskeleton Organization Actin Polymerization Or Depolymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Organelle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Movement Of Cell Or Subcellular Component Regulation Of Actin Nucleation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Assembly Axonogenesis Locomotion Positive Regulation Of Immune System Process Axon Development Cell Development Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Cellular Response To Stimulus Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Communication Positive Regulation Of Immune Response Neuron Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Axon Guidance Response To Stimulus Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cell Morphogenesis Involved In Differentiation Cell Projection Organization Signal Transduction Neuron Projection Development Regulation Of Cell Projection Organization Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Response To External Stimulus Cell Part Morphogenesis Regulation Of Immune Response Signaling Cell Surface Receptor Signaling Pathway	Vascular Endothelial Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Cytoskeleton Organization Actin Filament-based Process Lamellipodium Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Lamellipodium Assembly Actin Polymerization Or Depolymerization Positive Regulation Of Lamellipodium Organization Rac Protein Signal Transduction Actin Filament Organization Cytoskeleton Organization Regulation Of Lamellipodium Assembly Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Actin Cytoskeleton Organization Defense Response Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Innate Immune Response Actin Filament Polymerization Regulation Of Immune Response Movement Of Cell Or Subcellular Component Lamellipodium Assembly Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Organelle Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Cytoskeleton Organization Lamellipodium Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Positive Regulation Of Cellular Component Biogenesis Immune Response Regulation Of Immune System Process Organelle Organization Immune System Process Cellular Protein Complex Assembly Protein Polymerization Vesicle-mediated Transport Regulation Of Cell Projection Assembly Cell Projection Morphogenesis
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