DNMBP and CYFIP2

Number of citations of the paper that reports this interaction (PMID 14506234)
39

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		DNMBP	CYFIP2
Gene Name		dynamin binding protein	cytoplasmic FMR1 interacting protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Stack Cytoskeleton Cell Junction Synapse	Cytoplasm Cytosol Membrane Cell Junction Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction	Apoptotic Process Single Organismal Cell-cell Adhesion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ACTA1 ARHGAP17 BIN3 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2	20 interactors: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP FMR1 FXR1 FXR2 GAS7 NCK1 NCKAP1 PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A
Entrez ID		23268	26999
HPRD ID		10918	07556
Ensembl ID		ENSG00000107554	ENSG00000055163
Uniprot IDs		Q6XZF7	E7EVJ5 E7EW33 F5H583 Q96F07
PDB IDs		1UG1 1UHC 4GLM
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Cytoskeleton Organization Actin Polymerization Or Depolymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Organelle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Movement Of Cell Or Subcellular Component Regulation Of Actin Nucleation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Assembly Axonogenesis Locomotion Positive Regulation Of Immune System Process Axon Development Cell Development Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Cellular Response To Stimulus Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Communication Positive Regulation Of Immune Response Neuron Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Axon Guidance Response To Stimulus Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cell Morphogenesis Involved In Differentiation Cell Projection Organization Signal Transduction Neuron Projection Development Regulation Of Cell Projection Organization Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Response To External Stimulus Cell Part Morphogenesis Regulation Of Immune Response Signaling Cell Surface Receptor Signaling Pathway	Rac Protein Signal Transduction Movement Of Cell Or Subcellular Component Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Lamellipodium Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Lamellipodium Assembly Negative Regulation Of Protein Metabolic Process Actin Cytoskeleton Organization Positive Regulation Of Lamellipodium Organization Actin Filament-based Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Cellular Component Organization Regulation Of Actin Nucleation Regulation Of Lamellipodium Assembly Regulation Of Cellular Process Immune Response-regulating Signaling Pathway Cytoskeleton Organization Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Locomotion Cell Motility Lamellipodium Morphogenesis Negative Regulation Of Biosynthetic Process Lamellipodium Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Anatomical Structure Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cytoskeleton Organization System Development Cell Projection Organization Regulation Of Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Ras Protein Signal Transduction Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Somitogenesis Cell Migration Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Negative Regulation Of Translation
Tagcloud ?			als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar
Tagcloud (Difference) ?			als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar
Tagcloud (Intersection) ?