DNMBP and DNM1

Number of citations of the paper that reports this interaction (PMID 14506234)
39

Data Source:
HPRD (in vivo, in vitro)

		DNMBP	DNM1
Gene Name		dynamin binding protein	dynamin 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Stack Cytoskeleton Cell Junction Synapse	Microtubule Plasma Membrane Membrane Coat Extracellular Vesicular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding Protein Kinase Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding Nitric-oxide Synthase Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction	Endocytosis Receptor-mediated Endocytosis Endosome Organization Axon Guidance Receptor Internalization Ephrin Receptor Signaling Pathway Clathrin-mediated Endocytosis
Pathways			Retrograde neurotrophin signalling Signalling by NGF Formation of annular gap junctions Axon guidance Gap junction degradation Gap junction trafficking L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades EPH-ephrin mediated repulsion of cells Toll Like Receptor 4 (TLR4) Cascade Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		19 interactors: ACTA1 ARHGAP17 BIN3 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2	47 interactors: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GNB2L1 GRB2 GRIN1 GRIN2D ITSN1 KIAA1377 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		23268	1759
HPRD ID		10918	03851
Ensembl ID		ENSG00000107554	ENSG00000106976
Uniprot IDs		Q6XZF7	Q05193
PDB IDs		1UG1 1UHC 4GLM	1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Cytoskeleton Organization Actin Polymerization Or Depolymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Organelle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Movement Of Cell Or Subcellular Component Regulation Of Actin Nucleation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Assembly Axonogenesis Locomotion Positive Regulation Of Immune System Process Axon Development Cell Development Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Cellular Response To Stimulus Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Communication Positive Regulation Of Immune Response Neuron Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Axon Guidance Response To Stimulus Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cell Morphogenesis Involved In Differentiation Cell Projection Organization Signal Transduction Neuron Projection Development Regulation Of Cell Projection Organization Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Response To External Stimulus Cell Part Morphogenesis Regulation Of Immune Response Signaling Cell Surface Receptor Signaling Pathway	Endocytosis Vesicle-mediated Transport Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Cellular Component Assembly Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Membrane Organization Transport Axon Guidance Cell Projection Organization Regulation Of Signaling Neuron Projection Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemotaxis Synaptic Vesicle Transport Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Neuron Development Generation Of Neurons Membrane Tubulation Signaling Axonogenesis Anatomical Structure Development Protein Complex Assembly Neurogenesis Cell Communication Anatomical Structure Morphogenesis Locomotion Neurotrophin TRK Receptor Signaling Pathway Synaptic Vesicle Endocytosis Cell Morphogenesis Involved In Differentiation Axon Development Enzyme Linked Receptor Protein Signaling Pathway Synaptic Vesicle Recycling Regulation Of Signal Transduction Neurotrophin Signaling Pathway Regulation Of Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Positive Regulation Of Metabolic Process Neuron Differentiation Negative Regulation Of Endocytosis
Tagcloud ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Difference) ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Intersection) ?