DNMBP and RAPH1

Number of citations of the paper that reports this interaction (PMID 14506234)
39

Data Source:
HPRD (in vitro)

		DNMBP	RAPH1
Gene Name		dynamin binding protein	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Stack Cytoskeleton Cell Junction Synapse	Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Filopodium
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction	Cell-matrix Adhesion Signal Transduction Axon Extension
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ACTA1 ARHGAP17 BIN3 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2	3 interactors: DNMBP SIAH1 VASP
Entrez ID		23268	65059
HPRD ID		10918	12356
Ensembl ID		ENSG00000107554	ENSG00000173166
Uniprot IDs		Q6XZF7	C9K0J5 Q70E73
PDB IDs		1UG1 1UHC 4GLM	4GMV 4GN1
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Cytoskeleton Organization Actin Polymerization Or Depolymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Organelle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Movement Of Cell Or Subcellular Component Regulation Of Actin Nucleation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Assembly Axonogenesis Locomotion Positive Regulation Of Immune System Process Axon Development Cell Development Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Cellular Response To Stimulus Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Communication Positive Regulation Of Immune Response Neuron Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Axon Guidance Response To Stimulus Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cell Morphogenesis Involved In Differentiation Cell Projection Organization Signal Transduction Neuron Projection Development Regulation Of Cell Projection Organization Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Response To External Stimulus Cell Part Morphogenesis Regulation Of Immune Response Signaling Cell Surface Receptor Signaling Pathway	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Protein Destabilization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis
Tagcloud ?			away cdc42 colocalize cores cortactin degrade ecm egfp gelsolin holes invade invadopodia invadopodial lamellipodial lamellipodin localizes metalloproteinases periphery podosome podosomes potentiates prel1 protrusions punctae redistribution reorganizes supervillin sv tks5
Tagcloud (Difference) ?			away cdc42 colocalize cores cortactin degrade ecm egfp gelsolin holes invade invadopodia invadopodial lamellipodial lamellipodin localizes metalloproteinases periphery podosome podosomes potentiates prel1 protrusions punctae redistribution reorganizes supervillin sv tks5
Tagcloud (Intersection) ?