DNMBP and ARHGAP17

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		DNMBP	ARHGAP17
Description		dynamin binding protein	Rho GTPase activating protein 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Nuclear Body Synapse Anchoring Junction Presynapse	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding
	Biological Process	Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Cilium Assembly	Signal Transduction Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction
Pathways		CDC42 GTPase cycle	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Stent thrombosis in response to clopidogrel treatment ( 32472697)	Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		21 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 UBC VASP WASF1 WASL WIPF2	16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10
Entrez ID		23268	55114
HPRD ID		10918	12207
Ensembl ID		ENSG00000107554	ENSG00000140750
Uniprot IDs		A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7	Q68EM7
PDB IDs		1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Lamellipodium Cytoskeleton Actin Polymerization Or Depolymerization Supramolecular Fiber Organization Profilin Binding Focal Adhesion Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Actin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament Organization Filopodium Neuron Projection Development Positive Regulation Of Protein Polymerization Actin Cytoskeleton Organization SH3 Domain Binding Positive Regulation Of Cellular Component Organization Postsynapse SCAR Complex Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Polymerization Actin Filament-based Process Plasma Membrane Bounded Cell Projection Organization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein-containing Complex Assembly Regulation Of Postsynapse Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cellular Component Organization Regulation Of Actin Filament Length Actin Cytoskeleton Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Component Biogenesis Cell Projection Organization Cytoplasm Rac Protein Signal Transduction Positive Regulation Of Protein-containing Complex Assembly Cytosol Positive Regulation Of Lamellipodium Assembly Axon Guidance Neuron Projection Guidance Cell Projection Regulation Of Cell Projection Assembly Actin Filament Polymerization Extracellular Exosome Positive Regulation Of Lamellipodium Organization	Ephrin Receptor Binding Endocytosis Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Phosphotyrosine Residue Binding Import Into Cell Actin Filament-based Process Regulation Of Protein-containing Complex Assembly Regulation Of Cell Projection Organization Regulation Of Endocytosis Positive Regulation Of Supramolecular Fiber Organization Cytosol Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein-containing Complex Assembly Cell-cell Junction Positive Regulation Of Locomotion Regulation Of Actin Filament-based Process Positive Regulation Of Lamellipodium Organization Regulation Of Supramolecular Fiber Organization Regulation Of Cell-substrate Adhesion Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of MAPK Cascade SH2 Domain Binding Cytoskeleton Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Non-membrane Spanning Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Substrate Adhesion-dependent Cell Spreading Regulation Of Actin Filament Organization Phospholipase Activator Activity Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Lamellipodium Organization B Cell Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Positive Regulation Of Organelle Organization Positive Regulation Of Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Cell Adhesion Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Regulation Of Substrate Adhesion-dependent Cell Spreading Signal Transduction Regulation Of Organelle Organization Regulation Of Vesicle-mediated Transport Positive Regulation Of Cell Migration Leukocyte Activation Positive Regulation Of Cell Motility
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