TSC2 and RHEB

  • Number of citations of the paper that reports this interaction (PMID 15854902)
  • 168
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology, pull down)
  • HPRD (in vitro)

TSC2

RHEB

Gene Name tuberous sclerosis 2 Ras homolog enriched in brain
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: AKT1 AKT2 AKT3 CALM1 CCND1 CDKN1B ESR1 FBXL6 FBXW5 GRB2 GSK3B LNX1 MAPK1 MAPK3 MAPKAPK2 MDFI NEK1 PAM PIN1 PPP2CA PRKAA1 PTK2 RAB5A RABEP1 RHEB RPS6KA1 SFN SMAD2 SMAD3 SPERT TBC1D7 TK1 TSC1 UBE3A YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ 22 interactors: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF ECSIT FKBP8 MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RPS6KB1 RPTOR TSC1 TSC2
Entrez ID 7249 6009
HPRD ID 01850 03188
Ensembl ID ENSG00000103197 ENSG00000106615
Uniprot IDs P49815 Q15382
PDB IDs 1XTQ 1XTR 1XTS 3SEA 3T5G
Enriched GO Terms of Interacting Partners?
Tagcloud ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine  tuberous 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Difference) ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  yielded 
Tagcloud (Intersection) ?
tsc2  tuberous