TSC2 and FBXW5

  • Number of citations of the paper that reports this interaction (PMID 18381890)
  • 36
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (two hybrid, in vitro)

TSC2

FBXW5

Gene Name tuberous sclerosis 2 F-box and WD repeat domain containing 5
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: AKT1 AKT2 AKT3 CALM1 CCND1 CDKN1B ESR1 FBXL6 FBXW5 GRB2 GSK3B LNX1 MAPK1 MAPK3 MAPKAPK2 MDFI NEK1 PAM PIN1 PPP2CA PRKAA1 PTK2 RAB5A RABEP1 RHEB RPS6KA1 SFN SMAD2 SMAD3 SPERT TBC1D7 TK1 TSC1 UBE3A YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ 16 interactors: ADAMTSL4 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NL SASS6 SKP1 TRIM27 TSC2 UBE2R2
Entrez ID 7249 54461
HPRD ID 01850 10955
Ensembl ID ENSG00000103197 ENSG00000159069
Uniprot IDs P49815 Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine  tuberous 
autophagic  autophagy  brains  competes  cul4  da  dopaminergic  dysfunctional  dysregulated  exclusive  hydroxydopamine  implicating  l1  mortem  mtor  neurochem  neurodegeneration  ohda  opposition  os  oxi  parkinson  pathogenic  proteasomal  stabilize  stabilizes  tnfaip8  tsc2  tuberous 
Tagcloud (Difference) ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine 
autophagic  autophagy  brains  competes  cul4  da  dopaminergic  dysfunctional  dysregulated  exclusive  hydroxydopamine  implicating  l1  mortem  mtor  neurochem  neurodegeneration  ohda  opposition  os  oxi  parkinson  pathogenic  proteasomal  stabilize  stabilizes  tnfaip8 
Tagcloud (Intersection) ?
tsc2  tuberous