TSC2 and TSC1

  • Number of citations of the paper that reports this interaction (PMID 12869586)
  • 299
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, two hybrid, in vivo)

TSC2

TSC1

Gene Name tuberous sclerosis 2 tuberous sclerosis 1
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: AKT1 AKT2 AKT3 CALM1 CCND1 CDKN1B ESR1 FBXL6 FBXW5 GRB2 GSK3B LNX1 MAPK1 MAPK3 MAPKAPK2 MDFI NEK1 PAM PIN1 PPP2CA PRKAA1 PTK2 RAB5A RABEP1 RHEB RPS6KA1 SFN SMAD2 SMAD3 SPERT TBC1D7 TK1 TSC1 UBE3A YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ 23 interactors: AKT1 ATXN1 CCNB1 CDK1 EZR IKBKB KDM1A MSN NEFL NF2 NGFRAP1 PLK1 PRMT6 RDX RHEB TBC1D7 TSC2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 7249 7248
HPRD ID 01850 05594
Ensembl ID ENSG00000103197 ENSG00000165699
Uniprot IDs P49815 Q32NF0 Q86WV8 Q92574
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine  tuberous 
abnormally  autosomal  deprived  formations  glutamine  hamartin  immunosuppressant  impairments  indicators  lifespan  master  mechanistically  mtorc1  neurocognitive  neuropsychological  orally  physiologically  premature  rapamycin  s6  seizures  starvation  surrogate  tsc2  tuber  tuberin  tuberous  withdrawal 
Tagcloud (Difference) ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine 
abnormally  autosomal  deprived  formations  glutamine  hamartin  immunosuppressant  impairments  indicators  lifespan  master  mechanistically  mtorc1  neurocognitive  neuropsychological  orally  physiologically  premature  rapamycin  s6  seizures  starvation  surrogate  tuber  tuberin  withdrawal 
Tagcloud (Intersection) ?
tsc2  tuberous