Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TEC and PRLR
Number of citations of the paper that reports this interaction (PMID
11328862
)
7
Data Source:
HPRD
(in vitro, in vivo)
TEC
PRLR
Gene Name
tec protein tyrosine kinase
prolactin receptor
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Cell-cell Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Extracellular Region
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Endosome Lumen
Molecular Function
Non-membrane Spanning Protein Tyrosine Kinase Activity
Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
Metal Ion Binding
Prolactin Receptor Activity
Protein Binding
Peptide Hormone Binding
Protein Homodimerization Activity
Ornithine Decarboxylase Activator Activity
Metal Ion Binding
Biological Process
Adaptive Immune Response
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Platelet Activation
Cell Differentiation
Intracellular Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Fc-epsilon Receptor Signaling Pathway
Regulation Of Cell Proliferation
Tissue Regeneration
Innate Immune Response
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Steroid Biosynthetic Process
Cell Surface Receptor Signaling Pathway
Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
Embryo Implantation
Lactation
Regulation Of Cell Adhesion
Regulation Of Epithelial Cell Differentiation
Prolactin Signaling Pathway
T Cell Activation
Activation Of JAK2 Kinase Activity
Negative Regulation Of Apoptotic Process
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Mammary Gland Epithelial Cell Differentiation
Prostate Gland Growth
Mammary Gland Alveolus Development
Pathways
Signaling by SCF-KIT
Signaling by Interleukins
Fc epsilon receptor (FCERI) signaling
Cytokine Signaling in Immune system
FCERI mediated Ca+2 mobilization
Interleukin-3, 5 and GM-CSF signaling
Innate Immune System
Nuclear signaling by ERBB4
Cytokine Signaling in Immune system
Signaling by ERBB4
Prolactin receptor signaling
Growth hormone receptor signaling
Drugs
Somatropin recombinant
Fluoxymesterone
Diseases
GWAS
Crohn's disease (
23128233
)
Protein-Protein Interactions
30 interactors:
ARHGEF12
BMX
BTK
DOK1
ERBB2
FASLG
GNA12
IKBKG
JAK1
JAK2
KIT
LYN
PIK3R1
PIK3R2
PIK3R3
PIP4K2A
PIP5K1A
PLCG1
PLCG2
PLK4
PRLR
PTPN18
PTPN21
RHOA
SHC1
SOCS1
STAP1
TP53
VAV1
WAS
18 interactors:
CISH
CREBBP
CSH1
FBXW11
GH1
JAK2
NEK3
PPIA
PRL
PTPN11
SOCS2
SOCS3
TEC
VAV1
VAV2
YWHAG
YWHAZ
ZAP70
Entrez ID
7006
5618
HPRD ID
02786
01457
Ensembl ID
ENSG00000135605
ENSG00000113494
Uniprot IDs
P42680
P16471
PDB IDs
2LUL
1BP3
2LFG
3D48
3MZG
3N06
3N0P
3NCB
3NCC
3NCE
3NCF
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cell Surface Receptor Signaling Pathway
Intracellular Signal Transduction
Innate Immune Response
Fc Receptor Signaling Pathway
Immune Response
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune System Process
Regulation Of Immune Response
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Signal Transduction
Wound Healing
Immune Response-regulating Signaling Pathway
Response To Organic Substance
Signaling
Defense Response
Response To Wounding
Cell Communication
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Phosphate-containing Compound Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Organic Substance
Regulation Of Immune System Process
Cell Activation
Regulation Of Signaling
Regulation Of Catalytic Activity
Cellular Response To Stimulus
Peptidyl-tyrosine Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Kinase Activity
Response To Growth Factor
Cell Differentiation
Cellular Response To Peptide Hormone Stimulus
Growth Hormone Receptor Signaling Pathway
Cellular Response To Peptide
Cellular Response To Growth Hormone Stimulus
Movement Of Cell Or Subcellular Component
Phagocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Phosphorylation
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Response To Growth Hormone
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
JAK-STAT Cascade
Enzyme Linked Receptor Protein Signaling Pathway
Response To Peptide Hormone
Response To Peptide
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Intracellular Signal Transduction
Cellular Response To Hormone Stimulus
Cellular Response To Organonitrogen Compound
Regulation Of JAK-STAT Cascade
Response To Organonitrogen Compound
Regulation Of Signal Transduction
Response To Hormone
Cellular Response To Organic Substance
Regulation Of Signaling
Cell Surface Receptor Signaling Pathway
Signal Transduction
Regulation Of Intracellular Signal Transduction
Signaling
Cell Communication
Response To Organic Substance
Regulation Of Kinase Activity
Innate Immune Response
Immune System Process
Cellular Response To Stimulus
Immune Response
Regulation Of Body Fluid Levels
Wound Healing
Defense Response
Response To Stimulus
Negative Regulation Of JAK-STAT Cascade
Regulation Of Cellular Response To Insulin Stimulus
Response To Wounding
Blood Coagulation
Hemostasis
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Regulation Of Protein Kinase Activity
Positive Regulation Of Signal Transduction
Regulation Of Immune Response
Regulation Of Phosphorylation
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Cellular Protein Modification Process
Tagcloud
?
abolished
cdna
cdnas
changed
cis1
cis2
cis3
cis4
comparable
expressions
gland
glands
hint
inducible
jab
little
luciferase
mammary
myc
postpartum
prolactin
reporter
responsive
sh2
slightly
stat5
tagged
transfected
transiently
Tagcloud (Difference)
?
abolished
cdna
cdnas
changed
cis1
cis2
cis3
cis4
comparable
expressions
gland
glands
hint
inducible
jab
little
luciferase
mammary
myc
postpartum
prolactin
reporter
responsive
sh2
slightly
stat5
tagged
transfected
transiently
Tagcloud (Intersection)
?