TEC

Gene Name		tec protein tyrosine kinase
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Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Cell-cell Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding Lipid Binding Metal Ion Binding
	Biological Process	Adaptive Immune Response Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Platelet Activation Cell Differentiation Intracellular Signal Transduction Peptidyl-tyrosine Autophosphorylation Fc-epsilon Receptor Signaling Pathway Regulation Of Cell Proliferation Tissue Regeneration Innate Immune Response T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway
Pathways		Signaling by SCF-KIT Signaling by Interleukins Fc epsilon receptor (FCERI) signaling Cytokine Signaling in Immune system FCERI mediated Ca+2 mobilization Interleukin-3, 5 and GM-CSF signaling Innate Immune System
Drugs
Diseases
GWAS		Crohn's disease ( 23128233)
Protein-protein Interactions		30 interactors: ARHGEF12 BMX BTK DOK1 ERBB2 FASLG GNA12 IKBKG JAK1 JAK2 KIT LYN PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP5K1A PLCG1 PLCG2 PLK4 PRLR PTPN18 PTPN21 RHOA SHC1 SOCS1 STAP1 TP53 VAV1 WAS
Entrez ID		7006
HPRD ID		02786
Ensembl ID		ENSG00000135605
Uniprot IDs		P42680
PDB IDs		2LUL
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Surface Receptor Signaling Pathway Intracellular Signal Transduction Innate Immune Response Fc Receptor Signaling Pathway Immune Response Fc-epsilon Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune System Process Regulation Of Immune Response Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Signal Transduction Wound Healing Immune Response-regulating Signaling Pathway Response To Organic Substance Signaling Defense Response Response To Wounding Cell Communication Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Phosphate-containing Compound Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Organic Substance Regulation Of Immune System Process Cell Activation Regulation Of Signaling Regulation Of Catalytic Activity Cellular Response To Stimulus Peptidyl-tyrosine Phosphorylation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Kinase Activity Response To Growth Factor Cell Differentiation Cellular Response To Peptide Hormone Stimulus Growth Hormone Receptor Signaling Pathway Cellular Response To Peptide Cellular Response To Growth Hormone Stimulus Movement Of Cell Or Subcellular Component Phagocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Phosphorylation
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