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TEC and BMX
Number of citations of the paper that reports this interaction (PMID
12573241
)
7
Data Source:
HPRD
(in vitro)
TEC
BMX
Gene Name
tec protein tyrosine kinase
BMX non-receptor tyrosine kinase
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Cell-cell Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cytosol
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Molecular Function
Non-membrane Spanning Protein Tyrosine Kinase Activity
Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
Metal Ion Binding
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Signal Transducer Activity
Receptor Binding
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Adaptive Immune Response
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Platelet Activation
Cell Differentiation
Intracellular Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Fc-epsilon Receptor Signaling Pathway
Regulation Of Cell Proliferation
Tissue Regeneration
Innate Immune Response
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Adaptive Immune Response
Protein Phosphorylation
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Adhesion
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Mesoderm Development
Cell Differentiation
Intracellular Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Proliferation
Innate Immune Response
Protein Autophosphorylation
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Pathways
Signaling by SCF-KIT
Signaling by Interleukins
Fc epsilon receptor (FCERI) signaling
Cytokine Signaling in Immune system
FCERI mediated Ca+2 mobilization
Interleukin-3, 5 and GM-CSF signaling
Innate Immune System
Apoptotic cleavage of cellular proteins
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
Protein-Protein Interactions
30 interactors:
ARHGEF12
BMX
BTK
DOK1
ERBB2
FASLG
GNA12
IKBKG
JAK1
JAK2
KIT
LYN
PIK3R1
PIK3R2
PIK3R3
PIP4K2A
PIP5K1A
PLCG1
PLCG2
PLK4
PRLR
PTPN18
PTPN21
RHOA
SHC1
SOCS1
STAP1
TP53
VAV1
WAS
23 interactors:
APP
BCAR1
BTK
C12orf45
CASP3
CAV1
EGFR
ERBB2
FBXO25
ITK
KDR
PAK1
PTK2
PTPN21
RAP1A
RUFY1
RUFY2
SRC
STAT1
STAT3
STAT5A
TEC
TNFRSF1B
Entrez ID
7006
660
HPRD ID
02786
02111
Ensembl ID
ENSG00000135605
ENSG00000102010
Uniprot IDs
P42680
P51813
PDB IDs
2LUL
2EKX
2YS2
3SXR
3SXS
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cell Surface Receptor Signaling Pathway
Intracellular Signal Transduction
Innate Immune Response
Fc Receptor Signaling Pathway
Immune Response
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune System Process
Regulation Of Immune Response
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Signal Transduction
Wound Healing
Immune Response-regulating Signaling Pathway
Response To Organic Substance
Signaling
Defense Response
Response To Wounding
Cell Communication
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Phosphate-containing Compound Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Organic Substance
Regulation Of Immune System Process
Cell Activation
Regulation Of Signaling
Regulation Of Catalytic Activity
Cellular Response To Stimulus
Peptidyl-tyrosine Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Kinase Activity
Response To Growth Factor
Cell Differentiation
Cellular Response To Peptide Hormone Stimulus
Growth Hormone Receptor Signaling Pathway
Cellular Response To Peptide
Cellular Response To Growth Hormone Stimulus
Movement Of Cell Or Subcellular Component
Phagocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Protein Autophosphorylation
Cell Surface Receptor Signaling Pathway
Immune System Process
Peptidyl-tyrosine Phosphorylation
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Proliferation
Intracellular Signal Transduction
Response To Organic Substance
Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Cellular Response To Organic Substance
Response To Growth Factor
Regulation Of Immune Response
Fc Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Cellular Response To Organonitrogen Compound
Positive Regulation Of Cellular Metabolic Process
Immune Response-regulating Signaling Pathway
Response To Wounding
Defense Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Differentiation
Positive Regulation Of Metabolic Process
Response To Stress
Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Innate Immune Response
Response To Organonitrogen Compound
Cellular Response To Hormone Stimulus
Neurotrophin Signaling Pathway
Wound Healing
Regulation Of Cell Death
Signal Transduction
Peptidyl-amino Acid Modification
Response To Hormone
Response To Peptide Hormone
Immune Response
Protein Phosphorylation
Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Cell Activation
Signaling
Response To Peptide
Cell Communication
Growth Hormone Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Tagcloud
?
additive
androgen
attenuation
btk
chemo
confer
correlates
ctn06
docetaxel
dtx
dual
etk
grades
healing
herein
immortalized
impeded
independence
killing
never
pc3
perception
prostate
raf
sensitizer
tec
vegfr
wound
xenograft
Tagcloud (Difference)
?
additive
androgen
attenuation
btk
chemo
confer
correlates
ctn06
docetaxel
dtx
dual
etk
grades
healing
herein
immortalized
impeded
independence
killing
never
pc3
perception
prostate
raf
sensitizer
tec
vegfr
wound
xenograft
Tagcloud (Intersection)
?