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TEC and PTPN18
Number of citations of the paper that reports this interaction (PMID
15588985
)
37
Data Source:
HPRD
(in vitro)
TEC
PTPN18
Gene Name
tec protein tyrosine kinase
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Cell-cell Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Nucleus
Cytoplasm
Molecular Function
Non-membrane Spanning Protein Tyrosine Kinase Activity
Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
Metal Ion Binding
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Protein Binding
Biological Process
Adaptive Immune Response
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Platelet Activation
Cell Differentiation
Intracellular Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Fc-epsilon Receptor Signaling Pathway
Regulation Of Cell Proliferation
Tissue Regeneration
Innate Immune Response
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Protein Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Pathways
Signaling by SCF-KIT
Signaling by Interleukins
Fc epsilon receptor (FCERI) signaling
Cytokine Signaling in Immune system
FCERI mediated Ca+2 mobilization
Interleukin-3, 5 and GM-CSF signaling
Innate Immune System
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
Protein-Protein Interactions
30 interactors:
ARHGEF12
BMX
BTK
DOK1
ERBB2
FASLG
GNA12
IKBKG
JAK1
JAK2
KIT
LYN
PIK3R1
PIK3R2
PIK3R3
PIP4K2A
PIP5K1A
PLCG1
PLCG2
PLK4
PRLR
PTPN18
PTPN21
RHOA
SHC1
SOCS1
STAP1
TP53
VAV1
WAS
9 interactors:
ABL1
ARHGAP5
CSK
ERBB2
GAB1
PSTPIP1
PSTPIP2
SRC
TEC
Entrez ID
7006
26469
HPRD ID
02786
05961
Ensembl ID
ENSG00000135605
ENSG00000072135
Uniprot IDs
P42680
Q99952
PDB IDs
2LUL
2OC3
4GFU
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cell Surface Receptor Signaling Pathway
Intracellular Signal Transduction
Innate Immune Response
Fc Receptor Signaling Pathway
Immune Response
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune System Process
Regulation Of Immune Response
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Signal Transduction
Wound Healing
Immune Response-regulating Signaling Pathway
Response To Organic Substance
Signaling
Defense Response
Response To Wounding
Cell Communication
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Phosphate-containing Compound Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Organic Substance
Regulation Of Immune System Process
Cell Activation
Regulation Of Signaling
Regulation Of Catalytic Activity
Cellular Response To Stimulus
Peptidyl-tyrosine Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Kinase Activity
Response To Growth Factor
Cell Differentiation
Cellular Response To Peptide Hormone Stimulus
Growth Hormone Receptor Signaling Pathway
Cellular Response To Peptide
Cellular Response To Growth Hormone Stimulus
Movement Of Cell Or Subcellular Component
Phagocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Phosphorylation
Peptidyl-tyrosine Autophosphorylation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Innate Immune Response
ERBB Signaling Pathway
Immune Response-regulating Signaling Pathway
Protein Autophosphorylation
Fc Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response
Defense Response
Regulation Of Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of MAPK Cascade
Regulation Of ERK1 And ERK2 Cascade
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
Wound Healing
Regulation Of MAPK Cascade
Immune System Process
Regulation Of Immune System Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Immune Response-activating Cell Surface Receptor Signaling Pathway
Response To Wounding
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Regulation Of Cell Proliferation
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Catalytic Activity
Response To Organonitrogen Compound
Positive Regulation Of Phosphorylation
Regulation Of Cell-cell Adhesion
Axon Guidance
Positive Regulation Of Protein Modification Process
Peptidyl-amino Acid Modification
Regulation Of Intracellular Signal Transduction
Response To Oxidative Stress
Central Nervous System Development
Organ Development
Response To Peptide Hormone
Antigen Receptor-mediated Signaling Pathway
Phosphorylation
Intracellular Signal Transduction
Cellular Response To Organic Substance
Positive Regulation Of Protein Kinase Activity
Regulation Of Cell Activation
Cellular Response To Organonitrogen Compound
Tagcloud
?
able
al
authors
barcodes
barcoding
concept
dynamic
emerging
et
forms
gives
modifications
nature
oncogene
paper
pest
phosphatase
proteasomal
rather
refers
regulate
relay
rise
signals
throughout
trafficking
translational
ubiquitination
wang
Tagcloud (Difference)
?
able
al
authors
barcodes
barcoding
concept
dynamic
emerging
et
forms
gives
modifications
nature
oncogene
paper
pest
phosphatase
proteasomal
rather
refers
regulate
relay
rise
signals
throughout
trafficking
translational
ubiquitination
wang
Tagcloud (Intersection)
?