SULT1A3 and TK1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SULT1A3	TK1
Gene Name		sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	thymidine kinase 1, soluble
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Aryl Sulfotransferase Activity Sulfotransferase Activity	Thymidine Kinase Activity ATP Binding Zinc Ion Binding Nucleoside Kinase Activity Identical Protein Binding
	Biological Process	Catecholamine Metabolic Process Xenobiotic Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Steroid Metabolic Process Flavonoid Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Liver Development Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Response To Toxic Substance Skeletal Muscle Cell Proliferation Phosphorylation Response To Nutrient Levels Pyrimidine Nucleoside Salvage Small Molecule Metabolic Process Thymidine Metabolic Process Response To Copper Ion Digestive Tract Development Protein Homotetramerization Response To Cortisol Nucleobase-containing Small Molecule Metabolic Process Fetal Process Involved In Parturition DNA Biosynthetic Process
Pathways			Pyrimidine salvage reactions Pyrimidine metabolism Metabolism of nucleotides
Drugs			Dithioerythritol Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP KHDRBS2 NIF3L1 SHMT1 SMN1 TK1	159 interactors: A1BG A2M AAMP ABHD4 ACTB ACTL6B ACTR1B ADAMTS10 ADD1 AGAP1 ALAS1 ALB APLP1 APP ARFGAP1 ASNA1 ATG16L2 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 C19orf60 CARHSP1 CCDC115 CCDC90B CDC20 CDK1 CDK4 CDKN1A CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE6 CPSF3L CRIP2 CRMP1 CSAD DACT1 DALRD3 DCAF13 DDAH2 DEAF1 DMPK DOCK7 DRAP1 DUS2 DYNC1I1 EEF1A1 EIF3G EIF4A2 EIF6 EXT2 EZH2 F13A1 FAF1 FAM20C FBN3 FGB FLAD1 FST FZR1 GAPDH GDF9 GDI1 GLB1 GPCPD1 HADHB HERC3 HMGXB3 HSPBAP1 IER3IP1 IGHM IMMT INPP5K ITSN1 JADE1 JMJD1C KDM6B KIF21B KIF5A KLHL23 KLHL5 KMT2B LOC148413 LRIF1 MAGEA4 MAST2 MED31 METTL23 MKI67 MPP1 MPPED1 MRFAP1 MRPL37 MSH2 NEUROD2 NGFR NKIRAS2 NMT2 NRBP1 ODC1 PAAF1 PDE4DIP PKM PLD3 PLXNA3 PPP4C PROC PSME1 PTPN4 PTPRK QARS RBBP4 RBM48 RPA1 RPL13 RPS2 RUVBL1 RXRA SDF4 SEMA5B SEPT6 SETDB1 SEZ6L2 SMC5 SNX1 SP110 SULT1A3 SUMO3 TAF1C TCTEX1D2 THOC3 TIAM2 TLE1 TMSB4X TP53 TRIM46 TRMT2A TSC2 TTC38 TUBA1A TUBB2A TUBB3 TYK2 UNC119 UPF2 USP4 WDR18 WDR60 WDR73 WIZ ZBTB16 ZNF431 ZXDC
Entrez ID		6818	7083
HPRD ID		07199	01771
Ensembl ID		ENSG00000261052	ENSG00000167900
Uniprot IDs		P50224 Q1ET61	P04183
PDB IDs		1CJM 2A3R	1W4R 1XBT 2ORV 2WVJ
Enriched GO Terms of Interacting Partners?		Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Pteridine-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Homotetramerization Nitrogen Compound Metabolic Process Fetal Process Involved In Parturition Protein Tetramerization 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Cellular Component Assembly Collateral Sprouting In Absence Of Injury Dihydrobiopterin Metabolic Process L-serine Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Carnitine Biosynthetic Process Nucleobase-containing Compound Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Response To Cortisol Thymidine Metabolic Process Axon Choice Point Recognition Protein Homooligomerization Deoxyribonucleoside Monophosphate Biosynthetic Process Glycine Biosynthetic Process From Serine Neuron Remodeling Tetrahydrofolate Interconversion Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Cofactor Metabolic Process Folic Acid Metabolic Process Glycine Biosynthetic Process Purine Nucleobase Biosynthetic Process Serine Family Amino Acid Catabolic Process Carnitine Metabolic Process MRNA Processing Parturition Cellular Copper Ion Homeostasis Protein Oligomerization Amino-acid Betaine Metabolic Process Copper Ion Homeostasis Suckling Behavior Tetrahydrofolate Metabolic Process Response To Copper Ion Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle L-serine Metabolic Process MRNA Metabolic Process Neuron Maturation	Cellular Metabolic Process Regulation Of Protein Metabolic Process Cellular Protein Metabolic Process Developmental Process Anatomical Structure Development System Development Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Localization Metabolic Process Regulation Of Metabolic Process Organelle Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Protein Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Catabolic Process RNA Metabolic Process Negative Regulation Of Cell Cycle Posttranscriptional Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Platelet Degranulation Gene Expression Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cellular Process Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Cycle Process Mitotic Cell Cycle Process Axon Guidance Chromatin Organization Viral Process Programmed Cell Death Negative Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Organic Substance Mitotic Cell Cycle Cellular Response To Growth Factor Stimulus
Tagcloud ?		1a2 1e1 absent adjacent canc cyp1a1 cyp1a2 d1 decreases estrogen hydroxylation ihc limit melatonin mt1 ncanc oncostatic pilot positively positivity representative specimens stimulates sulfonation suppresses	american artiodactyla assigned block blot cattle chr conservative conserved cow electrophoresis erbb2 hybrid hybridization localization localized means mink nf1 pepa pig prkca rara representatives sheep southern swine synteny umph2
Tagcloud (Difference) ?		1a2 1e1 absent adjacent canc cyp1a1 cyp1a2 d1 decreases estrogen hydroxylation ihc limit melatonin mt1 ncanc oncostatic pilot positively positivity representative specimens stimulates sulfonation suppresses	american artiodactyla assigned block blot cattle chr conservative conserved cow electrophoresis erbb2 hybrid hybridization localization localized means mink nf1 pepa pig prkca rara representatives sheep southern swine synteny umph2
Tagcloud (Intersection) ?