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STK3 and GMCL1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
STK3
GMCL1
Description
serine/threonine kinase 3
germ cell-less 1, spermatogenesis associated
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Protein-containing Complex
Nucleus
Nuclear Matrix
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
Metal Ion Binding
Protein Serine Kinase Activity
Transcription Regulator Activator Activity
Protein Binding
Identical Protein Binding
Biological Process
Neural Tube Formation
Endocardium Development
Protein Phosphorylation
Protein Import Into Nucleus
Apoptotic Process
Signal Transduction
JNK Cascade
Central Nervous System Development
Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Gene Expression
Organ Growth
Hippo Signaling
Positive Regulation Of Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of JNK Cascade
Negative Regulation Of Organ Growth
Epithelial Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Protein Stabilization
Protein Tetramerization
Centrosome Separation
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Canonical Wnt Signaling Pathway
Primitive Hemopoiesis
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of Cell Differentiation Involved In Embryonic Placenta Development
Protein Localization To Centrosome
Negative Regulation Of Canonical Wnt Signaling Pathway
Hepatocyte Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Germ Cell Development
Spermatogenesis
Cell Differentiation
Pathways
Signaling by Hippo
Drugs
Fostamatinib
Diseases
GWAS
Depressive symptom improvement (
30468137
)
Heel bone mineral density (
30598549
)
Rosacea symptom severity (
29771307
)
Suicide behavior (
26079190
)
Atrial fibrillation (
28416818
29892015
30061737
)
Colorectal or endometrial cancer (
26621817
)
Red cell distribution width (
32888494
)
Whole brain grey matter density (
31530798
)
Interacting Genes
41 interacting genes:
AKT1
CASP3
CDK1
CNKSR1
CPNE1
DDAH2
EIF4EBP1
FAM9B
GABARAP
GABARAPL1
GAD1
GBP2
GMCL1
HSPE1
KEAP1
KHSRP
LATS2
LRRK2
MAP1LC3B
MAP1LC3C
MARK2
MBP
MOB3B
MOB4
MPP1
OGT
ORM2
PEX19
PIN1
QARS1
RAF1
RASSF4
SAV1
SLMAP
SNIP1
SULT2A1
TFPT
TRAF1
TRIM21
TRIM69
ZC3H7A
98 interacting genes:
APLF
APOL6
AXIN1
BEGAIN
BSCL2
BYSL
CCDC13
CCDC25
CDC37
CFAP298
CFAP410
CHIC2
CIB3
CLK2
CUL3
EHHADH
ELOA
EMD
EXOC3
FAM50B
FKBP1B
FLYWCH1
FOSL2
FOXR1
FRMD6
GAGE1
GAGE10
GAGE12B
GAGE12G
GAGE12I
GAGE12J
GAGE2A
GAGE2C
GAGE2E
GAGE5
GLRX3
GOLGA2
GRAMD1A
HYKK
IL17F
KANK2
KAT5
KIFC3
KLHL20
KPNA2
KRT75
LNX1
MID1
MID2
MINDY1
MORF4L1
MPPE1
MTRR
MYLIP
MYO5B
NEBL
NFIL3
NTAQ1
NUMA1
PARD6B
PARP16
PAX4
PBXIP1
PIBF1
PIH1D2
PPP1R18
PTPN7
QRICH1
RAD54B
RANBP3
RASA1
RNF4
RNMT
SHQ1
SLC15A3
SNX20
SPATA31J1
STK3
SUMO1
SUMO1P1
SYT17
SYT6
TBC1D1
TLK2
TMPO
TRIM13
TRIM21
TRIM38
TRIM54
TSG101
TSSC4
UBE2I
XAGE2
YY1
ZBTB24
ZMYM2
ZNF23
ZNF250
Entrez ID
6788
64395
HPRD ID
05433
13587
Ensembl ID
ENSG00000104375
ENSG00000087338
Uniprot IDs
A0A087WZ06
A0A384MR07
Q13188
Q53SE7
Q96IK5
PDB IDs
3WWS
4HKD
4L0N
4LG4
4LGD
4OH9
5BRM
5DH3
6AO5
6AR2
8A66
Enriched GO Terms of Interacting Partners
?
Cellular Response To Nitrogen Starvation
Autophagy Of Mitochondrion
Phosphatidylethanolamine Binding
Regulation Of Hippo Signaling
Cytoplasm
Mitophagy
Autophagosome
Cellular Response To Nutrient Levels
Autophagosome Assembly
Vacuole Organization
Cellular Response To Starvation
Autophagosome Organization
Regulation Of Intracellular Signal Transduction
Autophagy
Autophagosome Maturation
Positive Regulation Of Proteolysis
Intracellular Signal Transduction
Autophagosome Membrane
Response To Starvation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cytosol
Protein-containing Complex Disassembly
Negative Regulation Of Hippo Signaling
Hippo Signaling
Apoptotic Process
Macroautophagy
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Programmed Cell Death
Protein Binding
Cell Death
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Organ Growth
Signal Transduction
Protein-containing Complex Organization
Positive Regulation Of Protein Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Modification Process
Regulation Of Programmed Cell Death
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Response To Nutrient Levels
Response To Stress
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Pyroptotic Inflammatory Response
Regulation Of Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Proteasomal Protein Catabolic Process
Protein Serine Kinase Activity
Protein Binding
Positive Regulation Of Viral Life Cycle
Ubiquitin Protein Ligase Activity
PML Body
Protein Modification Process
Regulation Of Viral Process
Protein Localization To Cytoskeleton
Protein Modification By Small Protein Conjugation
Suppression Of Viral Release By Host
Regulation Of Viral Transcription
Negative Regulation Of Viral Transcription
Transcription Factor Binding
Protein Sumoylation
Cytoplasm
Post-translational Protein Modification
Small Protein Activating Enzyme Binding
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Viral Process
Modification-dependent Protein Catabolic Process
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