BPGM and GAPDH

Number of citations of the paper that reports this interaction (PubMedID 9308888)
0

Data Source:
HPRD (in vitro)

		BPGM	GAPDH
Description		bisphosphoglycerate mutase	glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Cytoplasm Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Nuclear Membrane Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome GAIT Complex Ribonucleoprotein Complex
	Molecular Function	Catalytic Activity Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity Isomerase Activity Intramolecular Phosphotransferase Activity	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor Transferase Activity Aspartic-type Endopeptidase Inhibitor Activity Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding Disordered Domain Specific Binding
	Biological Process	Carbohydrate Metabolic Process Glycolytic Process Nucleoside Phosphate Metabolic Process Respiratory Gaseous Exchange By Respiratory System Oxygen Transport Cellular Response To Stress Defense Response To Protozoan Erythrocyte Development Establishment Of Blood-brain Barrier Neuroinflammatory Response Carbohydrate Derivative Catabolic Process	Microtubule Cytoskeleton Organization Positive Regulation Of Cytokine Production Immune System Process Glucose Metabolic Process Glycolytic Process Regulation Of Translation Apoptotic Process Negative Regulation Of Endopeptidase Activity Regulation Of Macroautophagy Negative Regulation Of Translation Killing Of Cells Of Another Organism Positive Regulation Of Type I Interferon Production Peptidyl-cysteine S-trans-nitrosylation Positive Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein Stabilization Defense Response To Fungus Neuron Apoptotic Process Killing By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Type II Interferon
Pathways		Glycolysis	Glycolysis Gluconeogenesis
Drugs			NADH Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Xanthinol Copper Artenimol
Diseases		Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Blood protein levels ( 30072576)	Blood protein levels ( 30072576)
Interacting Genes		9 interacting genes: AKT1 ATF6 ATP4B CEL EGR2 EHD2 GAPDH GRB2 NEK3	92 interacting genes: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CEBPA CHP1 DUX4 DYNLL1 EGFR ERBB2 FBXO7 FKBP6 FOXP1 GADD45A GAS7 GOT2 GRIA2 GRM1 HES1 HNF4G HSPB2 HTT ITGB5 KARS1 KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 LINC01554 MAPK1 MTNR1A MYOC NFYC NR1H4 NUFIP2 OGT OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 PTPRF RAB2A RBM5 RPA2 RXFP4 S100A6 SERPINB9 SHANK3 SIAH1 SIRT1 SLC2A1 SLC2A4 SMARCA2 SMN1 SUMO4 TERF1 TINF2 TK1 TPPP TSC2 TXNIP USP25 WEE2-AS1 YWHAE YWHAQ
Entrez ID		669	2597
HPRD ID		01961	00713
Ensembl ID		ENSG00000172331	ENSG00000111640
Uniprot IDs		A0A024R782 P07738	P04406 V9HVZ4
PDB IDs		1T8P 2A9J 2F90 2H4X 2H4Z 2H52 2HHJ 3NFY 7N3R 7N3S 7THI 8X2S	1U8F 1ZNQ 3GPD 4WNC 4WNI 6ADE 6IQ6 6M61 6YND 6YNE 6YNF 6YNH 8DNS 8G12 8G13 8G14 8G15 8G16 8G17 8P5F
Enriched GO Terms of Interacting Partners?		Insulin-like Growth Factor Receptor Signaling Pathway ER-nucleus Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Epidermal Growth Factor Receptor Signaling Pathway T Cell Costimulation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Myelination Regulation Of TRNA Methylation Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Guanyl-nucleotide Exchange Factor Adaptor Activity Positive Regulation Of ATF6-mediated Unfolded Protein Response Positive Regulation Of Protein Localization To Endoplasmic Reticulum ERBB Signaling Pathway Response To Insulin-like Growth Factor Stimulus Mammalian Oogenesis Stage Regulation Of Response To Endoplasmic Reticulum Stress TRNA (guanine-N7)-methylation Cellular Response To Rapamycin Regulation Of Autophagy Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Endodeoxyribonuclease Activity Insulin Receptor Signaling Pathway Identical Protein Binding P-type Potassium:proton Transporter Activity Potassium:proton Exchanging ATPase Complex Acetylesterase Activity Rhombomere 3 Development Positive Regulation Of Schwann Cell Differentiation Brain Segmentation Myelination Axon Ensheathment Peptidyl-cysteine S-trans-nitrosylation Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Peptidyl-cysteine S-nitrosylase Activity Grb2-EGFR Complex Plasma Membrane Organization Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane TORC2 Complex Binding Glucose Metabolic Process Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process SREBP-SCAP Complex Retention In Endoplasmic Reticulum Sterol Ester Esterase Activity Regulation Of Schwann Cell Differentiation Peptidyl-cysteine S-nitrosylation GAIT Complex	Developmental Process Cellular Developmental Process Nucleus Cell Differentiation Regulation Of Programmed Cell Death Regulation Of Phosphorus Metabolic Process Shelterin Complex Regulation Of Cellular Component Organization Negative Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of DNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Signal Transduction Regulation Of Apoptotic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Nuclear Telomere Cap Complex Protein-containing Complex Regulation Of Cellular Localization Cellular Response To Stress Regulation Of Cellular Response To Stress Regulation Of Multicellular Organismal Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Localization Regulation Of DNA Metabolic Process Telomeric DNA Binding Telomere Capping Regulation Of Phosphorylation Nucleoplasm Regulation Of Developmental Process Negative Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Telomere Assembly Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Regulation Of Chromosome Organization Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Phosphate Metabolic Process Regulation Of Cell Population Proliferation Negative Regulation Of Biosynthetic Process Cytosol Positive Regulation Of Programmed Cell Death Positive Regulation Of Signaling Positive Regulation Of Chromosome Organization Positive Regulation Of Multicellular Organismal Process Regulation Of Cell Development Positive Regulation Of Cellular Component Organization System Development
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