NAT1 and CSMD1

  • Data Source: HiPPIP (Novel)

NAT1

CSMD1

Name N-acetyltransferase 1 CUB and Sushi multiple domains 1
Structure PDB 2IJA PDB 2EHF
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways None
GWAS
  • Femur bone mineral density x serum urate levels interaction ( 34046847 )
  • Metabolite levels ( 23823483 )
  • Night sleep phenotypes ( 27126917 )
  • Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171 )
  • A body shape index ( 34021172 )
  • Adolescent idiopathic scoliosis ( 31417091 )
  • Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065 )
  • Aggressiveness in attention deficit hyperactivity disorder ( 27021288 )
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360 )
  • Alzheimer's disease (cognitive decline) ( 23535033 )
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757 )
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 )
  • Anti-saccade response ( 29064472 )
  • Atypical femoral fracture in phosphonate treatment ( 31006051 )
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885 )
  • Bitter alcoholic beverage consumption ( 31046077 )
  • Blood pressure measurement (high sodium intervention) ( 24165912 )
  • Body size at age 10 ( 32376654 )
  • Cannabis dependence symptom count ( 27028160 )
  • Cerebrospinal fluid clusterin levels ( 26545630 )
  • Chronic bronchitis and chronic obstructive pulmonary disease ( 25241909 )
  • Chronotype ( 30696823 )
  • Clostridioides difficle infection ( 33841421 )
  • Coronary artery aneurysm in Kawasaki disease ( 27171184 )
  • Dementia and core Alzheimer's disease neuropathologic changes ( 25188341 )
  • Diisocyanate-induced asthma ( 25918132 )
  • Eating disorders (purging via substances) ( 23568457 )
  • Emphysema imaging phenotypes ( 26030696 )
  • Emphysema-related traits ( 20709820 )
  • Endometriosis ( 23472165 )
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678 )
  • Estimated glomerular filtration rate after 5 years in renal transplantation (donor effect) ( 30920136 )
  • Estimated glomerular filtration rate reduction (30%) ( 30955190 )
  • Estrogen level change in anastrozole-treated breast cancer ( 32701512 )
  • Facial morphology ( 31763980 )
  • Gastroesophageal reflux disease ( 27485664 )
  • Gut microbiota (beta diversity) ( 27723756 )
  • Gut microbiota relative abundance (Dorea) ( 33208821 )
  • Hand grip strength ( 27325353 )
  • HDL cholesterol ( 21347282 )
  • HDL cholesterol levels in HIV infection ( 33109212 )
  • Health literacy ( 31250787 )
  • High chromosomal aberration frequency (chromatid type) ( 31586183 )
  • Homeostasis model assessment of insulin resistance ( 33381925 )
  • Illicit drug use ( 23942779 )
  • Immune response to smallpox vaccine (IL-6) ( 22542470 )
  • Inflammatory skin disease ( 25574825 )
  • Insulin resistance/response ( 21901158 )
  • Intake of total sugars ( 31005972 )
  • Iris color (b* coordinate) ( 29109912 )
  • joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033 )
  • Lateral ventricle temporal horn volume ( 31530798 )
  • Leukocyte telomere length ( 32109421 )
  • Loneliness ( 27629369 )
  • Longevity ( 30294719 )
  • Lung cancer ( 34062886 )
  • Major depressive disorder ( 34099189 )
  • Major depressive disorder x sex interaction ( 34099189 )
  • Malaria ( 31844061 )
  • Menarche (age at onset) ( 25231870 )
  • Morning person ( 30696823 )
  • Multiple keratinocyte cancers ( 28081215 )
  • Multiple sclerosis ( 19010793 )
  • Negative urgency ( 30718321 )
  • Neuritic plaque ( 25188341 )
  • Neurocognitive impairment in HIV-1 infection (dichotomous) ( 28447399 )
  • Nicotine dependence symptom count ( 25555482 )
  • Night sleep phenotypes ( 27126917 )
  • Obesity-related traits ( 23251661 )
  • Osteoarthritis biomarkers ( 25057126 )
  • Percentage gas trapping ( 26030696 )
  • Periodontitis (CDC/AAP) ( 24024966 )
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311 )
  • Post-traumatic stress disorder ( 25456346 )
  • Postburn hypertrophic scarring severity ( 26366535 )
  • Psychosis proneness (revised social anhedonia scale) ( 28525603 )
  • Pulmonary function decline ( 22424883 )
  • Pursuit maintenance gain ( 29064472 )
  • QRS interval (sulfonylurea treatment interaction) ( 27958378 )
  • Raw vegetable consumption ( 32066663 )
  • Refractive error ( 32231278 )
  • Response to bupropion in depression ( 27622933 )
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693 )
  • Resting heart rate ( 28270201 )
  • Schizophrenia ( 21926974 22688191 25056061 27922604 28991256 29483656 30285260 )
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486 )
  • Serum metabolite concentrations in chronic kidney disease ( 33838163 )
  • Serum selenium levels ( 23698163 )
  • Severe malaria ( 29381699 )
  • Severe malaria (adjusted for sickle cell variant rs334) ( 29381699 )
  • Spatial memory ( 31596458 )
  • Systolic blood pressure in sickle cell anemia ( 24058526 )
  • Tea consumption ( 31046077 )
  • Toenail selenium levels ( 25343990 )
  • Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429 )
  • Triptolide cytotoxicity ( 26121980 )
  • Type 2 diabetes ( 31049640 )
  • Urinary albumin excretion ( 30220432 )
  • Uterine fibroids ( 28836065 )
  • Waist circumference adjusted for body mass index ( 34021172 )
  • Waist-hip ratio ( 23966867 )
Novel Interactors 1 novel interactors: CSMD1 1 novel interactors: NAT1
Interacting Genes 2 interacting genes: NAA10 SNTA1 None recorded
Entrez ID 9 64478
HPRD ID 00149 10523
Ensembl ID ENSG00000171428 ENSG00000183117
Uniprot IDs F5H5R8 P18440 Q400J6 Q59FF8 Q96PZ7
PDB IDs 2IJA 2PQT 2EHF
GO Terms Enriched among Interactors