DTNA and SNTG1

Number of citations of the paper that reports this interaction (PMID 10747910)
24

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		DTNA	SNTG1
Gene Name		dystrobrevin, alpha	syntrophin, gamma 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Sarcolemma Protein Complex Synapse	Nucleus Cytoplasm Cytoskeleton Syntrophin Complex Ruffle Membrane
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Actin Binding Protein C-terminus Binding
	Biological Process	Striated Muscle Contraction Signal Transduction Synaptic Transmission Neuromuscular Synaptic Transmission	Cell Communication
Pathways
Drugs
Diseases
GWAS			Pulmonary function ( 17903307)
Protein-Protein Interactions		14 interactors: ACTA1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 SYNC SYNM UTRN	11 interactors: ADRA1D DGKZ DMD DTNA DTNB KCNA4 SNAP23 STXBP3 TGFBR1 UBC VPS45
Entrez ID		1837	54212
HPRD ID		03141	16373
Ensembl ID		ENSG00000134769	ENSG00000147481
Uniprot IDs		A8K541 B7Z3X3 M0QYX6 Q9Y4J8	Q9NSN8
PDB IDs		2E5R
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Myotube Cell Development Actin-myosin Filament Sliding Muscle Filament Sliding Cardiac Muscle Cell Action Potential Intermediate Filament-based Process Actin-mediated Cell Contraction Muscle Fiber Development Positive Regulation Of Cell-matrix Adhesion Muscle Organ Development Myotube Differentiation Actin Filament-based Movement Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Muscle Structure Development Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development System Development Regulation Of Muscle Contraction Striated Muscle Cell Development Synaptic Transmission Regulation Of Dopamine Receptor Signaling Pathway Skeletal Muscle Thin Filament Assembly Olfactory Nerve Development Muscle Cell Development Regulation Of Skeletal Muscle Contraction Actin Filament-based Process Skeletal Myofibril Assembly Neurotransmitter Receptor Metabolic Process Regulation Of Cell-substrate Adhesion Platelet Dense Granule Organization	Cell-cell Signaling Signaling Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Transmission Wound Healing Cell Activation Response To Wounding Leukocyte Degranulation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Exocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Response To Stimulus Vesicle Docking Striated Muscle Contraction Hormone Secretion Protein Complex Assembly Blood Coagulation Membrane Docking Hemostasis Hormone Transport Mitotic DNA Damage Checkpoint Negative Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Establishment Of Glial Blood-brain Barrier Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Secretion By Cell Response To Stress Negative Regulation Of Peptidyl-cysteine S-nitrosylation Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Body Fluid Levels Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization DNA Damage Checkpoint Leukocyte Activation Involved In Immune Response Secretion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Mitotic Cell Cycle Checkpoint
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