Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SLCO1A2 and PDZD3
Number of citations of the paper that reports this interaction (PMID
15553237
)
5
Data Source:
HPRD
(two hybrid)
SLCO1A2
PDZD3
Gene Name
solute carrier organic anion transporter family, member 1A2
PDZ domain containing 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Cytosol
Brush Border
Subapical Complex
Apical Part Of Cell
Molecular Function
Organic Anion Transmembrane Transporter Activity
Protein Binding
Protein C-terminus Binding
Ion Channel Inhibitor Activity
Guanylate Cyclase Inhibitor Activity
Biological Process
Bile Acid Metabolic Process
Organic Anion Transport
Bile Acid And Bile Salt Transport
Sodium-independent Organic Anion Transport
Small Molecule Metabolic Process
Transmembrane Transport
Ion Transport
Water Transport
Receptor Guanylyl Cyclase Signaling Pathway
Response To Toxic Substance
CGMP-mediated Signaling
Negative Regulation Of CGMP Biosynthetic Process
Negative Regulation Of Guanylate Cyclase Activity
Pathways
Bile acid and bile salt metabolism
Metabolism of lipids and lipoproteins
Recycling of bile acids and salts
Transport of vitamins, nucleosides, and related molecules
SLC-mediated transmembrane transport
Transport of organic anions
Drugs
Diseases
GWAS
Bilirubin levels (
19414484
)
Methotrexate phramacokinetics (acute lymphoblastic leukemia) (
19901119
)
Progressive supranuclear palsy (
21685912
)
Protein-Protein Interactions
4 interactors:
PDZD3
PDZK1
SLC9A3R1
SLC9A3R2
17 interactors:
ABCC2
ASAP3
CACNA1S
CFTR
GUCY2C
PTGIR
SLC15A1
SLC15A2
SLC22A3
SLC22A4
SLC22A5
SLC22A9
SLC41A3
SLCO1A2
SLCO1C1
SLCO3A1
SPRYD7
Entrez ID
6579
79849
HPRD ID
09112
06191
Ensembl ID
ENSG00000084453
ENSG00000172367
Uniprot IDs
P46721
B0YJ61
Q86UT5
PDB IDs
2V90
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of CGMP Biosynthetic Process
Renal Phosphate Ion Absorption
Negative Regulation Of Guanylate Cyclase Activity
Monocarboxylic Acid Transport
Glutathione Transport
Negative Regulation Of Sodium:proton Antiporter Activity
Renal Sodium Ion Transport
Cellular Phosphate Ion Homeostasis
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Sodium:proton Antiporter Activity
Carboxylic Acid Transport
Organic Acid Transport
Negative Regulation Of Sodium Ion Transmembrane Transport
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Ion Transport
Bile Acid Secretion
CGMP-mediated Signaling
Receptor Guanylyl Cyclase Signaling Pathway
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Ion Transmembrane Transport
Oligopeptide Transport
Carnitine Transport
Organic Anion Transport
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Renal Absorption
Regulation Of Proton Transport
Phosphate Ion Homeostasis
Microvillus Assembly
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Microvillus Organization
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Quaternary Ammonium Group Transport
Regulation Of CGMP Biosynthetic Process
Negative Regulation Of Lyase Activity
Regulation Of Ion Transport
Regulation Of Excretion
Monovalent Inorganic Cation Transport
Anion Transport
Regulation Of Sodium Ion Transmembrane Transporter Activity
Cyclic-nucleotide-mediated Signaling
Bile Acid And Bile Salt Transport
Regulation Of CGMP Metabolic Process
Positive Regulation Of Protein Targeting To Membrane
Dopamine Receptor Signaling Pathway
Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Nucleotide Metabolic Process
Transmembrane Transport
Ion Transport
Ion Transmembrane Transport
Sodium-independent Organic Anion Transport
Anion Transport
Organic Anion Transport
Anion Transmembrane Transport
Drug Transport
Monocarboxylic Acid Transport
Quaternary Ammonium Group Transport
Transport
Cation Transmembrane Transport
Drug Transmembrane Transport
Carboxylic Acid Transport
Organic Acid Transport
Antibiotic Transport
Toxin Transport
Ammonium Transmembrane Transport
Organic Cation Transport
Cation Transport
Oligopeptide Transport
Ammonium Transport
Response To Drug
Inorganic Anion Transport
Carnitine Transmembrane Transport
Carnitine Transport
Lipid Transport
Lipid Localization
Monovalent Inorganic Cation Transport
Dipeptide Transport
Histamine Uptake
Positive Regulation Of ARF GTPase Activity
Short-chain Fatty Acid Import
Positive Regulation Of Voltage-gated Chloride Channel Activity
Positive Regulation Of Intestinal Epithelial Structure Maintenance
Quorum Sensing Involved In Interaction With Host
Sodium-dependent Organic Cation Transport
Fatty Acid Transport
Regulation Of Intestinal Epithelial Structure Maintenance
Prostaglandin Transport
Peptide Transport
Hormone Transport
Extraocular Skeletal Muscle Development
Oligopeptide Transmembrane Transport
Regulation Of Chloride Transport
Amide Transport
Iodide Transport
Thyroid Hormone Transport
Transepithelial Chloride Transport
Cellular Chloride Ion Homeostasis
Tagcloud
?
abcc
abcc1
abcc3
abcc4
abcc5
abcc6
accessibility
astrocytic
chemoresistance
formerly
gliomas
mrp1
mrp6
oatp
oatp1a2
oatp1b1
oatp1b3
oatp1c1
oatp2b1
oatp4a1
oligoastrocytomas
oligodendrogliomas
pcrs
portions
pumps
transporters
Tagcloud (Difference)
?
abcc
abcc1
abcc3
abcc4
abcc5
abcc6
accessibility
astrocytic
chemoresistance
formerly
gliomas
mrp1
mrp6
oatp
oatp1a2
oatp1b1
oatp1b3
oatp1c1
oatp2b1
oatp4a1
oligoastrocytomas
oligodendrogliomas
pcrs
portions
pumps
transporters
Tagcloud (Intersection)
?