SLC15A1 and PDZD3

Number of citations of the paper that reports this interaction (PMID 15553237)
5

Data Source:
HPRD (two hybrid)

		SLC15A1	PDZD3
Gene Name		solute carrier family 15 (oligopeptide transporter), member 1	PDZ domain containing 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Cytosol Brush Border Subapical Complex Apical Part Of Cell
	Molecular Function	Proton-dependent Oligopeptide Secondary Active Transmembrane Transporter Activity Peptide:proton Symporter Activity	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity
	Biological Process	Transport Ion Transport Digestion Protein Transport Proton Transport Oligopeptide Transmembrane Transport Transmembrane Transport	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance CGMP-mediated Signaling Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Proton/oligonucleotide cotransporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
Protein-Protein Interactions		1 interactors: PDZD3	17 interactors: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7
Entrez ID		6564	79849
HPRD ID		02768	06191
Ensembl ID		ENSG00000088386	ENSG00000172367
Uniprot IDs		B2CQT6 P46059	B0YJ61 Q86UT5
PDB IDs			2V90
Enriched GO Terms of Interacting Partners?		Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Cyclic-nucleotide-mediated Signaling Regulation Of CGMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Water Transport Fluid Transport Regulation Of Cyclase Activity Second-messenger-mediated Signaling Response To Toxic Substance	Transmembrane Transport Ion Transport Ion Transmembrane Transport Sodium-independent Organic Anion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Drug Transport Monocarboxylic Acid Transport Quaternary Ammonium Group Transport Transport Cation Transmembrane Transport Drug Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Antibiotic Transport Toxin Transport Ammonium Transmembrane Transport Organic Cation Transport Cation Transport Oligopeptide Transport Ammonium Transport Response To Drug Inorganic Anion Transport Carnitine Transmembrane Transport Carnitine Transport Lipid Transport Lipid Localization Monovalent Inorganic Cation Transport Dipeptide Transport Histamine Uptake Positive Regulation Of ARF GTPase Activity Short-chain Fatty Acid Import Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Intestinal Epithelial Structure Maintenance Quorum Sensing Involved In Interaction With Host Sodium-dependent Organic Cation Transport Fatty Acid Transport Regulation Of Intestinal Epithelial Structure Maintenance Prostaglandin Transport Peptide Transport Hormone Transport Extraocular Skeletal Muscle Development Oligopeptide Transmembrane Transport Regulation Of Chloride Transport Amide Transport Iodide Transport Thyroid Hormone Transport Transepithelial Chloride Transport Cellular Chloride Ion Homeostasis
Tagcloud ?		absorbed absorption accumulated acids bile carrier circadian clock consumed dark digested feeding governs interfered intestinal mammals nocturnally oscillates oscillation peaked pept1 peroxisome pparalpha proliferator proton start suppressing transactivation transporter
Tagcloud (Difference) ?		absorbed absorption accumulated acids bile carrier circadian clock consumed dark digested feeding governs interfered intestinal mammals nocturnally oscillates oscillation peaked pept1 peroxisome pparalpha proliferator proton start suppressing transactivation transporter
Tagcloud (Intersection) ?