SLC15A1

Description		solute carrier family 15 member 1
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GO Annotations	Cellular Component	Plasma Membrane Brush Border Membrane Apical Plasma Membrane
	Molecular Function	Proton-dependent Oligopeptide Secondary Active Transmembrane Transporter Activity Symporter Activity Peptide:proton Symporter Activity Transmembrane Transporter Activity Oligopeptide Transmembrane Transporter Activity Tripeptide Transmembrane Transporter Activity Dipeptide Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Oligopeptide Transport Protein Transport Peptide Transport Transmembrane Transport Dipeptide Import Across Plasma Membrane Tripeptide Import Across Plasma Membrane Proton Transmembrane Transport
Pathways		Proton/oligopeptide cotransporters
Drugs		Ampicillin Phenoxymethylpenicillin Cefotaxime Oxacillin Benzylpenicillin Ceftriaxone Benzoic acid Dexibuprofen
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Educational attainment ( 25201988) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) QRS interval (sulfonylurea treatment interaction) ( 27958378) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: NHERF4 USP7
Entrez ID		6564
HPRD ID		02768
Ensembl ID		ENSG00000088386
Uniprot IDs		B2CQT6 P46059
PDB IDs		7PMW 7PMX 7PN1
Enriched GO Terms of Interacting Partners?		Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of CGMP-mediated Signaling Guanylate Cyclase Inhibitor Activity Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Receptor Guanylyl Cyclase Signaling Pathway Regulation Of CGMP-mediated Signaling Ion Channel Inhibitor Activity Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Gluconeogenesis Negative Regulation Of Intracellular Signal Transduction K48-linked Deubiquitinase Activity Ubiquitin-specific Protease Binding Deubiquitinase Activity Water Transport Apical Junction Complex Protein-membrane Adaptor Activity Fluid Transport Nucleotide-excision Repair Negative Regulation Of Signal Transduction Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity Negative Regulation Of Signaling Brush Border P53 Binding Cysteine-type Deubiquitinase Activity Protein Deubiquitination Autophagosome Assembly Regulation Of TORC1 Signaling Negative Regulation Of TOR Signaling TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Glucose Metabolic Process Apical Part Of Cell Response To Toxic Substance Autophagosome Organization Negative Regulation Of Autophagy Regulation Of Telomere Maintenance PML Body
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