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METTL17 and SF3B4
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
METTL17
SF3B4
Gene Name
methyltransferase like 17
splicing factor 3b, subunit 4, 49kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Mitochondrion
Ribosome
Nucleoplasm
Spliceosomal Complex
U12-type Spliceosomal Complex
Molecular Function
Copper Ion Binding
Protein Binding
Methyltransferase Activity
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Translation
Methylation
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Height (
20881960
18391951
)
Protein-Protein Interactions
14 interactors:
ATXN1
ATXN1L
CALCOCO2
CEP70
KRT40
MAPK6
MDFI
MID2
PNMA1
SF3B4
SPERT
TFIP11
TRAF1
TRIP6
42 interactors:
APBB1
BAG3
BAIAP2
BMPR1A
CHERP
CWF19L2
DDX17
DDX42
EFTUD2
EWSR1
FKBP1A
FRK
GRB2
HNRNPD
HNRNPF
HNRNPH1
HNRNPUL1
HSPB7
ILF3
ITSN1
MAPK9
METTL17
NCK2
NUB1
PPP1R16B
PRPF40A
RBM39
RBM4
SEC24D
SF1
SF3B2
SRSF6
SS18L1
STK19
SUMO4
TCAF1
TCERG1
UBASH3A
UBC
WBP4
WDR77
ZCCHC10
Entrez ID
64745
10262
HPRD ID
13379
12028
Ensembl ID
ENSG00000165792
ENSG00000143368
Uniprot IDs
Q9H7H0
B3KUJ0
Q15427
PDB IDs
1X5T
1X5U
Enriched GO Terms of Interacting Partners
?
Lung Alveolus Development
Regulation Of RNA Metabolic Process
Spliceosomal Complex Disassembly
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription Factor Import Into Nucleus
Positive Regulation Of Hematopoietic Stem Cell Proliferation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Release Of Cytoplasmic Sequestered NF-kappaB
RNA Processing
Negative Regulation Of Gene Expression
Regulation Of Protein Import Into Nucleus
Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of Biosynthetic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Localization To Microtubule
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Regulation Of Protein Localization To Nucleus
Regulation Of Nucleocytoplasmic Transport
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
MAPK Cascade
MRNA Splicing, Via Spliceosome
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Intracellular Signal Transduction
Lung Development
Respiratory Tube Development
Regulation Of Intracellular Protein Transport
Negative Regulation Of Viral Release From Host Cell
Regulation Of Signal Transduction
Signal Transduction By Phosphorylation
Negative Regulation Of Viral Entry Into Host Cell
Respiratory System Development
Trophoblast Giant Cell Differentiation
RNA Processing
RNA Splicing
MRNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Circadian Regulation Of Translation
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Development
Cellular Response To Growth Factor Stimulus
Regulation Of ERBB Signaling Pathway
Response To Growth Factor
Negative Regulation Of Protein Metabolic Process
Immune System Process
Response To External Stimulus
Regulation Of Circadian Rhythm
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neuron Development
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Signal Transduction
Regulation Of Cellular Process
Stress-activated MAPK Cascade
Fc Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
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