KIF22 and PJA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIF22	PJA1
Gene Name		kinesin family member 22	praja ring finger 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Chromatin Nucleus Nucleoplasm Cytoplasm Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion	Cytoplasm
	Molecular Function	DNA Binding Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	DNA Repair Microtubule-based Movement Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Metaphase Plate Congression Blood Coagulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Protein Ubiquitination Protein Catabolic Process
Pathways		MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)
Protein-Protein Interactions		6 interactors: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL	36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440
Entrez ID		3835	64219
HPRD ID		04445	02335
Ensembl ID		ENSG00000079616	ENSG00000181191
Uniprot IDs		B7Z9T5 Q14807	Q8NG27
PDB IDs		2EDU 3BFN	2L0B
Enriched GO Terms of Interacting Partners?			Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway See more
Tagcloud ?		advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Difference) ?		advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Intersection) ?