SCN4A and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SCN4A	ERBB2IP
Gene Name		sodium channel, voltage gated, type IV alpha subunit	erbb2 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Voltage-gated Sodium Channel Activity	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions	Signaling by ERBB2
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALM1 DLG1 DLG2 DLG3 ERBB2IP INADL SLC9A3R1 SNTA1 SNTB1 SNTB2	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		6329	55914
HPRD ID		04912	06090
Ensembl ID		ENSG00000007314	ENSG00000112851
Uniprot IDs		P35499	B4DIP2 Q96RT1
PDB IDs			1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Sodium Ion Transmembrane Transport Muscle Contraction Receptor Clustering Nucleotide Phosphorylation Muscle System Process Regulation Of Sodium Ion Transport Regulation Of Phosphatase Activity Regulation Of Ion Transmembrane Transport Regulation Of Dephosphorylation Establishment Or Maintenance Of Cell Polarity Synaptic Transmission Regulation Of Ion Transport Cellular Protein Localization Cellular Localization Negative Regulation Of Protein Kinase B Signaling Regulation Of Phosphorus Metabolic Process Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Tight Junction Assembly Membrane Organization Negative Regulation Of Transmembrane Transport Negative Regulation Of Phosphatase Activity Cell-cell Signaling Protein Localization To Membrane Negative Regulation Of Dephosphorylation Protein Localization Apical Junction Assembly Regulation Of Heart Rate Organophosphate Metabolic Process Regulation Of Cardiac Muscle Contraction Regulation Of Vasoconstriction By Circulating Norepinephrine Renal Phosphate Ion Absorption Regulation Of Striated Muscle Contraction Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Negative Regulation Of Sodium:proton Antiporter Activity Basal Protein Localization Glutathione Transport Cell-cell Junction Assembly Regulation Of Catalytic Activity Regulation Of Protein Kinase B Signaling Signaling Nucleotide Metabolic Process Cell Communication Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?