SCN4A and INADL

Number of citations of the paper that reports this interaction (PMID 16637659)
18

Data Source:
HPRD (in vitro)

		SCN4A	INADL
Gene Name		sodium channel, voltage gated, type IV alpha subunit	InaD-like (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Tight Junction Apical Plasma Membrane Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Sodium Channel Activity	Protein Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Cell Junction Assembly Intracellular Signal Transduction Cell-cell Junction Organization Tight Junction Assembly
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions	Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: CALM1 DLG1 DLG2 DLG3 ERBB2IP INADL SLC9A3R1 SNTA1 SNTB1 SNTB2	28 interactors: ASIC3 BAI1 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3
Entrez ID		6329	10207
HPRD ID		04912	04434
Ensembl ID		ENSG00000007314	ENSG00000132849
Uniprot IDs		P35499	Q8NI35
PDB IDs			1VF6 2D92 2DAZ 2DB5 2DLU 2DM8 2DMZ 2EHR
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Sodium Ion Transmembrane Transport Muscle Contraction Receptor Clustering Nucleotide Phosphorylation Muscle System Process Regulation Of Sodium Ion Transport Regulation Of Phosphatase Activity Regulation Of Ion Transmembrane Transport Regulation Of Dephosphorylation Establishment Or Maintenance Of Cell Polarity Synaptic Transmission Regulation Of Ion Transport Cellular Protein Localization Cellular Localization Negative Regulation Of Protein Kinase B Signaling Regulation Of Phosphorus Metabolic Process Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Tight Junction Assembly Membrane Organization Negative Regulation Of Transmembrane Transport Negative Regulation Of Phosphatase Activity Cell-cell Signaling Protein Localization To Membrane Negative Regulation Of Dephosphorylation Protein Localization Apical Junction Assembly Regulation Of Heart Rate Organophosphate Metabolic Process Regulation Of Cardiac Muscle Contraction Regulation Of Vasoconstriction By Circulating Norepinephrine Renal Phosphate Ion Absorption Regulation Of Striated Muscle Contraction Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Negative Regulation Of Sodium:proton Antiporter Activity Basal Protein Localization Glutathione Transport Cell-cell Junction Assembly Regulation Of Catalytic Activity Regulation Of Protein Kinase B Signaling Signaling Nucleotide Metabolic Process Cell Communication Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity	Synaptic Transmission Cell-cell Signaling Membrane Depolarization Regulation Of Membrane Potential Neurological System Process Cation Transmembrane Transport Ion Transmembrane Transport Neuron-neuron Synaptic Transmission Regulation Of Ion Transmembrane Transport Metal Ion Transport Ion Transport Cation Transport Signaling Cell Communication Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Transmembrane Transport Regulation Of Ion Transport Neuromuscular Process Regulation Of Neurological System Process Glutamate Receptor Signaling Pathway Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Potassium Ion Import Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Cell-cell Junction Organization Startle Response Monovalent Inorganic Cation Transport Directional Locomotion Membrane Depolarization During Action Potential Membrane Hyperpolarization Single-organism Behavior Gephyrin Clustering Transport Tight Junction Assembly Nervous System Development Regulation Of Resting Membrane Potential Postsynaptic Membrane Assembly Transmission Of Nerve Impulse Behavior Potassium Ion Transmembrane Transport Protein Localization To Membrane Glial Cell Differentiation Postsynaptic Density Protein 95 Clustering Neurogenesis Membrane Depolarization During Cardiac Muscle Cell Action Potential Apical Junction Assembly Potassium Ion Transport Response To Mechanical Stimulus
Tagcloud ?		blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?		blotting chorionic cloned cs deoxyribonuclease evolutionarily genomes gh homologue hypersensitive immediately implies insert kb kilobases linkage loci locus orientation p1 physically pig pituitary somatomammotropin sug transcriptase trip ubiquitously unlike	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?