S100A1 and S100A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		S100A1	S100A3
Description		S100 calcium binding protein A1	S100 calcium binding protein A3
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Golgi Apparatus Cytosol Sarcoplasmic Reticulum Z Disc M Band A Band I Band Protein-containing Complex	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Metal Ion Binding Calcium-dependent Protein Binding ATPase Binding	Calcium Ion Binding Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Vasodilation Positive Regulation Of Sprouting Angiogenesis
Pathways		ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand
Drugs		Olopatadine
Diseases
GWAS
Interacting Genes		36 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BEX3 BIK CACYBP CAPZA1 CEP20 CLCF1 CNTF CTF1 DES FKBP4 GFAP GJA1 IFNB1 IL11 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A3 S100A4 S100B S100P S100Z SYN1 TP53	7 interacting genes: LNX1 RARA RARG S100A1 S100A10 S100A2 S100Z
Entrez ID		6271	6274
HPRD ID		01489	01507
Ensembl ID		ENSG00000160678	ENSG00000188015
Uniprot IDs		A0A0S2Z4H2 P23297	P33764
PDB IDs		2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89	1KSO 3NSI 3NSK 3NSL 3NSO
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Binding S100 Protein Binding Transition Metal Ion Binding Identical Protein Binding Calcium Ion Binding Calcium Ion-transporting ATPase Complex Negative Regulation Of Blood Circulation Regulation Of Blood Circulation Regulation Of System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Cellular Response To Actinomycin D Cell Surface Receptor Signaling Pathway Via STAT Cell Body Response To Actinomycin D Cellular Response To UV-C Ciliary Neurotrophic Factor Receptor Binding Sarcoplasmic Reticulum Membrane Positive Regulation Of Cell Population Proliferation Regulation Of Cardiac Muscle Cell Membrane Potential Cytokine Activity Intercalated Disc Muscle System Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Antibiotic Negative Regulation Of ATP-dependent Activity RAGE Receptor Binding Developmental Process Relaxation Of Cardiac Muscle Response To Hypoxia Cell Activation Response To UV-C Sarcoplasmic Reticulum Response To Decreased Oxygen Levels Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Sarcoplasmic Reticulum Calcium Ion Transport Modulation Of Chemical Synaptic Transmission Regulation Of Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Response To Oxygen Levels Astrocyte Activation Astrocyte Development Intracellular Calcium Ion Homeostasis Regulation Of Programmed Cell Death Regulation Of Heart Contraction Relaxation Of Muscle Cellular Response To UV Negative Regulation Of Heart Contraction Circadian Behavior Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Rhythmic Behavior	Calcium-dependent Protein Binding Trachea Cartilage Development Glandular Epithelial Cell Development Growth Plate Cartilage Development Columnar/cuboidal Epithelial Cell Development RNA Polymerase II Transcription Regulator Complex Embryonic Camera-type Eye Development Cartilage Development Involved In Endochondral Bone Morphogenesis Retinoic Acid Receptor Signaling Pathway Face Development Calcium Ion Binding Negative Regulation Of Cartilage Development Regulation Of Myelination MRNA Transcription By RNA Polymerase II Nuclear Receptor Activity Limb Development MRNA Transcription Cellular Response To Retinoic Acid Connective Tissue Development Bone Development Regulation Of Cartilage Development Sertoli Cell Fate Commitment Metal Ion Binding Camera-type Eye Development Neural Tube Closure Regulation Of Nervous System Development Tube Closure Response To Retinoic Acid Multicellular Organism Growth Nuclear Receptor-mediated Signaling Pathway Cartilage Development AnxA2-p11 Complex Eye Development Tube Formation Epithelial Cell Development Growth Plate Cartilage Chondrocyte Growth Regulation Of Multicellular Organismal Development Hormone-mediated Signaling Pathway Harderian Gland Development Positive Regulation Of Plasma Membrane Repair Embryonic Organ Development Sensory Organ Development Chondroblast Differentiation Chondrocyte Hypertrophy Protein Homodimerization Activity Ventricular Cardiac Muscle Cell Differentiation Reproductive Structure Development Retinoic Acid-responsive Element Binding Positive Regulation Of T-helper 2 Cell Differentiation Heterocyclic Compound Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?