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S100A1 and IL11
Number of citations of the paper that reports this interaction (PubMedID
34933172
)
0
Data Source:
BioGRID
(pull down)
S100A1
IL11
Description
S100 calcium binding protein A1
interleukin 11
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Golgi Apparatus
Cytosol
Sarcoplasmic Reticulum
Z Disc
M Band
A Band
I Band
Protein-containing Complex
Extracellular Region
Extracellular Space
Cytoplasm
Molecular Function
Calcium Ion Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
S100 Protein Binding
Metal Ion Binding
Calcium-dependent Protein Binding
ATPase Binding
Cytokine Activity
Interleukin-11 Receptor Binding
Protein Binding
Growth Factor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Heart Contraction
Substantia Nigra Development
Intracellular Signal Transduction
Vasodilation
Positive Regulation Of Sprouting Angiogenesis
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
B Cell Differentiation
Megakaryocyte Differentiation
Positive Regulation Of Peptidyl-serine Phosphorylation
Interleukin-11-mediated Signaling Pathway
Positive Regulation Of MAPK Cascade
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Hormone Secretion
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Complement-dependent Cytotoxicity
Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
ER-Phagosome pathway
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
MyD88 deficiency (TLR2/4)
IRAK4 deficiency (TLR2/4)
Regulation of TLR by endogenous ligand
IL-6-type cytokine receptor ligand interactions
Drugs
Olopatadine
Diseases
GWAS
Appendicular lean mass (
33097823
)
Osteoarthritis (hip) (
30374069
)
Response to antidepressants (
20360315
)
Interacting Genes
36 interacting genes:
ACTA1
AGER
ANXA6
ATP2A2
BEX3
BIK
CACYBP
CAPZA1
CEP20
CLCF1
CNTF
CTF1
DES
FKBP4
GFAP
GJA1
IFNB1
IL11
MDM2
NIF3L1
PGM1
PLB1
PLEKHF2
PLN
PPID
PYGM
REL
RYR1
S100A2
S100A3
S100A4
S100B
S100P
S100Z
SYN1
TP53
7 interacting genes:
IL11RA
MAGEA11
S100A1
S100A6
S100B
S100P
UBQLN2
Entrez ID
6271
3589
HPRD ID
01489
00980
Ensembl ID
ENSG00000160678
ENSG00000095752
Uniprot IDs
A0A0S2Z4H2
P23297
A8K3F7
P20809
PDB IDs
2L0P
2LHL
2LLS
2LLT
2LLU
2LP2
2LP3
2LUX
2M3W
5K89
4MHL
6O4O
8DPS
8DPT
8DPU
8DPV
8DPW
8QY4
Enriched GO Terms of Interacting Partners
?
Calcium-dependent Protein Binding
S100 Protein Binding
Transition Metal Ion Binding
Identical Protein Binding
Calcium Ion Binding
Calcium Ion-transporting ATPase Complex
Negative Regulation Of Blood Circulation
Regulation Of Blood Circulation
Regulation Of System Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Cellular Response To Actinomycin D
Cell Surface Receptor Signaling Pathway Via STAT
Cell Body
Response To Actinomycin D
Cellular Response To UV-C
Ciliary Neurotrophic Factor Receptor Binding
Sarcoplasmic Reticulum Membrane
Positive Regulation Of Cell Population Proliferation
Regulation Of Cardiac Muscle Cell Membrane Potential
Cytokine Activity
Intercalated Disc
Muscle System Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Cellular Response To Antibiotic
Negative Regulation Of ATP-dependent Activity
RAGE Receptor Binding
Developmental Process
Relaxation Of Cardiac Muscle
Response To Hypoxia
Cell Activation
Response To UV-C
Sarcoplasmic Reticulum
Response To Decreased Oxygen Levels
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Sarcoplasmic Reticulum Calcium Ion Transport
Modulation Of Chemical Synaptic Transmission
Regulation Of Apoptotic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Response To Oxygen Levels
Astrocyte Activation
Astrocyte Development
Intracellular Calcium Ion Homeostasis
Regulation Of Programmed Cell Death
Regulation Of Heart Contraction
Relaxation Of Muscle
Cellular Response To UV
Negative Regulation Of Heart Contraction
Circadian Behavior
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Rhythmic Behavior
Calcium-dependent Protein Binding
S100 Protein Binding
Calcium Ion Binding
Protein Homodimerization Activity
Identical Protein Binding
Extracellular Region
Ruffle
Negative Regulation Of G Protein-coupled Receptor Internalization
Interleukin-11 Receptor Activity
Interleukin-11 Binding
Axonogenesis
Negative Regulation Of Clathrin-dependent Endocytosis
Response To Anesthetic
Response To Methylmercury
Sympathetic Neuron Projection Extension
Interleukin-11-mediated Signaling Pathway
Negative Regulation Of Skeletal Muscle Cell Differentiation
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Tagcloud (Intersection)
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