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S100A1 and ATP2A2
Number of citations of the paper that reports this interaction (PMID
12804600
)
12
Data Source:
HPRD
(in vitro, in vivo)
S100A1
ATP2A2
Gene Name
S100 calcium binding protein A1
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Sarcoplasmic Reticulum
Z Disc
M Band
Neuron Projection
Protein Complex
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Intercalated Disc
Longitudinal Sarcoplasmic Reticulum
Membrane
Sarcoplasmic Reticulum
Platelet Dense Tubular Network Membrane
Sarcoplasmic Reticulum Membrane
Calcium Ion-transporting ATPase Complex
Molecular Function
Calcium Ion Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
S100 Protein Binding
Calcium-dependent Protein Binding
ATPase Binding
Calcium-transporting ATPase Activity
Calcium Ion Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
Enzyme Binding
S100 Protein Binding
Metal Ion Binding
Calcium-transporting ATPase Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Heart Contraction
Substantia Nigra Development
Intracellular Signal Transduction
Positive Regulation Of Voltage-gated Calcium Channel Activity
Regulation Of The Force Of Heart Contraction
Cellular Calcium Ion Homeostasis
ER-nucleus Signaling Pathway
Cell Adhesion
Blood Coagulation
Metabolic Process
Epidermis Development
Positive Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Ion Transmembrane Transport
Negative Regulation Of Heart Contraction
Transmembrane Transport
Relaxation Of Cardiac Muscle
Sarcoplasmic Reticulum Calcium Ion Transport
Calcium Ion Transmembrane Transport
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Calcium Ion Transport From Cytosol To Endoplasmic Reticulum
Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways
Ion transport by P-type ATPases
Ion channel transport
Pre-NOTCH Processing in Golgi
Platelet homeostasis
Reduction of cytosolic Ca++ levels
Signaling by NOTCH
Pre-NOTCH Expression and Processing
Platelet calcium homeostasis
Drugs
Olopatadine
Diseases
GWAS
Protein quantitative trait loci (
18464913
)
Protein-Protein Interactions
24 interactors:
ACTA1
AGER
ANXA6
ATP2A2
CACYBP
CAPZA1
DES
FKBP4
GFAP
GJA1
MDM2
NIF3L1
PGM1
PLB1
PLEKHF2
PLN
PPID
PYGM
RYR1
S100A2
S100A4
S100B
S100P
SYN1
9 interactors:
BCL2
CAMK2A
HGS
IRS1
IRS2
MDM2
PLN
S100A1
SPP1
Entrez ID
6271
488
HPRD ID
01489
00161
Ensembl ID
ENSG00000160678
ENSG00000174437
Uniprot IDs
P23297
P16615
PDB IDs
2L0P
2LHL
2LLS
2LLT
2LLU
2LP2
2LP3
2LUX
Enriched GO Terms of Interacting Partners
?
Muscle System Process
Response To Abiotic Stimulus
Regulation Of Cardiac Muscle Cell Contraction
Regulation Of Muscle Contraction
Regulation Of Heart Contraction
Regulation Of Cardiac Muscle Cell Membrane Potential
Protein Complex Assembly
Sarcoplasmic Reticulum Calcium Ion Transport
Regulation Of Cardiac Muscle Contraction
Muscle Contraction
Relaxation Of Cardiac Muscle
Regulation Of Striated Muscle Contraction
Glycogen Catabolic Process
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Polysaccharide Catabolic Process
Calcium Ion Transport
Relaxation Of Muscle
Striated Muscle Tissue Development
Negative Regulation Of Heart Contraction
Skeletal Muscle Fiber Development
Response To Hormone
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Response To Metal Ion
Muscle Tissue Development
Cellular Component Assembly
Myotube Cell Development
Regulation Of Cellular Localization
Cellular Carbohydrate Catabolic Process
Regulation Of The Force Of Heart Contraction
Actin-myosin Filament Sliding
Muscle Filament Sliding
Response To Wounding
Regulation Of Ion Homeostasis
Regulation Of Actin Filament-based Process
Cellular Metal Ion Homeostasis
Cellular Response To Alkaloid
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Astrocyte Differentiation
Cytosolic Calcium Ion Homeostasis
Cellular Cation Homeostasis
Actin-mediated Cell Contraction
Cellular Ion Homeostasis
Response To Peptide Hormone
Cardiac Conduction
Tissue Development
Negative Regulation Of Striated Muscle Tissue Development
Steroid Hormone Receptor Complex Assembly
Calcium Ion Transport From Cytosol To Endoplasmic Reticulum
Positive Regulation Of Schwann Cell Proliferation
Positive Regulation Of Transport
Regulation Of Cellular Localization
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Hormone
Regulation Of Calcium Ion Transport
Regulation Of Ion Transport
Defense Response
Response To Organic Substance
Innate Immune Response
Negative Regulation Of Ion Transport
Response To Organonitrogen Compound
Positive Regulation Of Fatty Acid Beta-oxidation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Negative Regulation Of Transport
Positive Regulation Of Glycogen Biosynthetic Process
Cellular Response To Stimulus
Response To Peptide Hormone
Phosphatidylinositol-mediated Signaling
Intracellular Signal Transduction
Immune Response-regulating Signaling Pathway
Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Fatty Acid Oxidation
Response To Steroid Hormone
Regulation Of Transmembrane Transporter Activity
Response To Peptide
Cell Surface Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Growth Hormone Receptor Signaling Pathway
Immune System Process
Cellular Response To Fibroblast Growth Factor Stimulus
Signal Transduction
Response To Fibroblast Growth Factor
Positive Regulation Of Lipid Catabolic Process
Cellular Response To Growth Hormone Stimulus
Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Secretion
Positive Regulation Of Fatty Acid Metabolic Process
Response To Ischemia
Regulation Of Glycogen Biosynthetic Process
Regulation Of Fatty Acid Oxidation
Neurotrophin Signaling Pathway
Regulation Of Mitochondrial Membrane Permeability
Fc-epsilon Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Establishment Of Protein Localization
Response To Stimulus
Signaling
Tagcloud
?
ablation
ad
ascertain
astrocytosis
burden
collectively
demonstration
detrimental
elucidated
gfap
gsk3beta
iba1
identifies
indirectly
microgliosis
modulates
neuroinflammation
normalizing
pathobiology
pc12
plaque
po4
psapp
ryanodine
ryr
sensor
twelve
undetectable
uses
Tagcloud (Difference)
?
ablation
ad
ascertain
astrocytosis
burden
collectively
demonstration
detrimental
elucidated
gfap
gsk3beta
iba1
identifies
indirectly
microgliosis
modulates
neuroinflammation
normalizing
pathobiology
pc12
plaque
po4
psapp
ryanodine
ryr
sensor
twelve
undetectable
uses
Tagcloud (Intersection)
?