S100A6 and PEX5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		S100A6	PEX5
Gene Name		S100 calcium binding protein A6	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nuclear Envelope Cytoplasm Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		11 interactors: ANXA11 ANXA2 CACYBP FKBP4 GAPDH MDM2 PEX5 PPID S100B SUGT1 TP53	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		6277	5830
HPRD ID		00237	02684
Ensembl ID		ENSG00000197956	ENSG00000139197
Uniprot IDs		P06703	B4DR50 B4E0T2 P50542
PDB IDs		1K8U 1K96 1K9K 1K9P	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Cellular Response To UV Protein Complex Assembly Cellular Response To Light Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Tetramerization Cellular Response To Oxygen Levels Response To UV Cellular Response To Radiation Response To Abiotic Stimulus Regulation Of Protein Oligomerization Cellular Component Assembly Protein Localization Immune Response Immune System Process Regulation Of Signal Transduction By P53 Class Mediator Mitotic Cell Cycle Process Positive Regulation Of Transport Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Mitochondrial Membrane Organization Establishment Of Protein Localization Response To Hypoxia Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Neuron Apoptotic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Antibiotic Innate Immune Response Regulation Of Cell Death Chaperone-mediated Protein Folding Response To Metal Ion Neuron Death Regulation Of Protein Complex Assembly Response To Light Stimulus Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Steroid Hormone Receptor Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Cellular Response To UV-C Cellular Response To Vitamin B1 Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-amino Acid Modification Protein Peptidyl-prolyl Isomerization Regulation Of Fibroblast Proliferation Apoptotic Process Protein Targeting Signal Transduction In Response To DNA Damage	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		125i annexin ascites ca2 calcyclin cellulose chromatography chymotrypsin database dehydrogenase depended digested eat ehrlich evidenced extracts gel glyceraldehyde homogeneity ions labelled overlay p30 phenyl purified search sepharose similarity spleen	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		125i annexin ascites ca2 calcyclin cellulose chromatography chymotrypsin database dehydrogenase depended digested eat ehrlich evidenced extracts gel glyceraldehyde homogeneity ions labelled overlay p30 phenyl purified search sepharose similarity spleen	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?