S100A6 and CACYBP

Number of citations of the paper that reports this interaction (PubMedID 12042313)
0

Data Source:
HPRD (in vivo)

		S100A6	CACYBP
Description		S100 calcium binding protein A6	calcyclin binding protein
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Extracellular Matrix Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Cell Body Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Monoatomic Ion Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Metal Ion Binding Calcium-dependent Protein Binding	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding
	Biological Process	Signal Transduction Axonogenesis Monoatomic Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation	Heart Development Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		50 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO FAM25A FAM25C FAM25G FKBP4 FLT3LG GAPDH GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL19 IL2 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 KITLG LEP MDM2 OFD1 PEX5 PPID PRL S100B SUGT1 THPO TP53	22 interacting genes: BEX3 CCR2 CD8A CEBPA ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1 SNCA
Entrez ID		6277	27101
HPRD ID		00237	07316
Ensembl ID		ENSG00000197956	ENSG00000116161
Uniprot IDs		P06703	Q9HB71
PDB IDs		1K8U 1K96 1K9K 1K9P 2M1K 4YBH	1X5M 2A25 2A26
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Positive Regulation Of Leukocyte Proliferation Leukocyte Differentiation Cell Activation Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Immune System Process Leukocyte Activation Cytokine Receptor Binding Regulation Of Multicellular Organismal Process Lymphocyte Activation Signal Transduction Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Lymphocyte Activation Regulation Of Lymphocyte Activation Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Regulation Of Receptor Signaling Pathway Via JAK-STAT Immune Response Positive Regulation Of Receptor Signaling Pathway Via STAT Positive Regulation Of Cell Activation Lymphocyte Differentiation Mononuclear Cell Differentiation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cell Activation Positive Regulation Of Developmental Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Cell Surface Receptor Signaling Pathway Via JAK-STAT Lymphocyte Proliferation Positive Regulation Of Cytokine Production Regulation Of Developmental Process Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of T Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Leukocyte Proliferation Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of T Cell Activation T Cell Activation	Identical Protein Binding Regulation Of Apoptotic Process Calcium-dependent Protein Binding Regulation Of Programmed Cell Death Regulation Of Protein Stability Protein Catabolic Process S100 Protein Binding Calcium Ion Binding Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Apoptotic Process Positive Regulation Of Defense Response Cell Death Programmed Cell Death Perinuclear Region Of Cytoplasm Proteasomal Protein Catabolic Process Positive Regulation Of Inflammatory Response Protein-containing Complex Regulation Of Protein Ubiquitination Amyloid Fibril Formation Negative Regulation Of Apoptotic Process Nucleus Negative Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Regulation Of Immune System Process Proteolysis Involved In Protein Catabolic Process Protein Homodimerization Activity Positive Regulation Of Protein Localization To Nucleolus Tau Protein Binding Regulation Of Signal Transduction Cytosol Regulation Of Biological Quality Macromolecule Catabolic Process Positive Regulation Of Synaptic Transmission Positive Regulation Of Cell Communication Positive Regulation Of Signaling Sperm Plasma Membrane Long-term Synaptic Potentiation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Defense Response Intracellular Signaling Cassette Neuronal Cell Body Regulation Of Protein Localization To Nucleolus Nucleoplasm RAGE Receptor Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Population Proliferation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
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