MPP1 and ACER1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MPP1	ACER1
Description		MAGUK p55 scaffold protein 1	alkaline ceramidase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Cell-cell Junction Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite Cell Projection	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	GMP Kinase Activity Signaling Receptor Binding Protein Binding	Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Metal Ion Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Epidermis Development Response To Alkaline PH Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Cell Differentiation Keratinocyte Differentiation Sphingosine Biosynthetic Process Ceramide Catabolic Process Sebaceous Gland Development Cellular Response To Calcium Ion
Pathways		Sensory processing of sound by outer hair cells of the cochlea	Sphingolipid catabolism
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes		46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GPRASP3 GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	1 interacting genes: MPP1
Entrez ID		4354	125981
HPRD ID		02370	12496
Ensembl ID		ENSG00000130830	ENSG00000167769
Uniprot IDs		B4E325 Q00013	Q8TDN7
PDB IDs		2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction TOR Signaling Ribosomal Protein S6 Kinase Activity N-acylsphingosine Amidohydrolase Activity	GMP Kinase Activity GDP Metabolic Process Stereocilium Regulation Of Neutrophil Chemotaxis Cortical Cytoskeleton GMP Metabolic Process Regulation Of Neutrophil Migration Positive Regulation Of Activated T Cell Proliferation T Cell Costimulation Regulation Of Activated T Cell Proliferation Regulation Of Granulocyte Chemotaxis
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