MPP1 and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		MPP1	ERBB2IP
Gene Name		membrane protein, palmitoylated 1, 55kDa	erbb2 interacting protein
Image
Gene Ontology Annotations	Cellular Component	Intracellular Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Guanylate Kinase Activity Protein Binding	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation Regulation Of Neutrophil Chemotaxis	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways			Signaling by ERBB2
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Protein-Protein Interactions		19 interactors: AMOTL2 ATP5C1 DNPEP ERBB2IP GADD45A GSK3B GYPC HNRNPD KLHL12 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 STK3 STUB1 TK1 ZAK	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		4354	55914
HPRD ID		02370	06090
Ensembl ID		ENSG00000130830	ENSG00000112851
Uniprot IDs		B4E325 Q00013	B4DIP2 Q96RT1
PDB IDs		2EJY 2EV8 3NEY	1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Communication Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Phosphorylation Intracellular Signal Transduction Regulation Of JNK Cascade Positive Regulation Of Cellular Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stimulus Intracellular Transport Positive Regulation Of Transferase Activity Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Fetal Process Involved In Parturition Negative Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Binding Golgi Vesicle Transport Positive Regulation Of Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?