MPP1 and PRIMPOL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MPP1	PRIMPOL
Description		MAGUK p55 scaffold protein 1	primase and DNA directed polymerase
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GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Cell-cell Junction Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite Cell Projection	DNA-directed RNA Polymerase Complex Nucleus Replication Fork Chromosome Mitochondrion Mitochondrial Matrix
	Molecular Function	GMP Kinase Activity Signaling Receptor Binding Protein Binding	Chromatin Binding DNA-directed DNA Polymerase Activity DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity Manganese Ion Binding DNA Polymerase Activity Metal Ion Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	DNA-templated DNA Replication Mitochondrial DNA Replication DNA Replication, Synthesis Of Primer DNA Repair DNA Damage Response Response To UV Translesion Synthesis Replication Fork Processing Error-prone Translesion Synthesis Mitochondrial DNA Repair R-loop Processing
Pathways		Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GPRASP3 GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	6 interacting genes: CDKN2D MPP1 NAV1 PSMA1 RPA1 USP36
Entrez ID		4354	201973
HPRD ID		02370	08742
Ensembl ID		ENSG00000130830	ENSG00000164306
Uniprot IDs		B4E325 Q00013	A0A5S6SZ32 Q96LW4
PDB IDs		2EJY 2EV8 3NEY	5L2X 5N85 5N8A 7JK1 7JKL 7JKP 7JL8 7JLG
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction TOR Signaling Ribosomal Protein S6 Kinase Activity N-acylsphingosine Amidohydrolase Activity
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