MPP1 and DNPEP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MPP1	DNPEP
Gene Name		membrane protein, palmitoylated 1, 55kDa	aspartyl aminopeptidase
Image
Gene Ontology Annotations	Cellular Component	Intracellular Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium	Nucleus Nucleoplasm Cytoplasm Blood Microparticle
	Molecular Function	Guanylate Kinase Activity Protein Binding	Aminopeptidase Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation Regulation Of Neutrophil Chemotaxis	Proteolysis Peptide Metabolic Process
Pathways
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
Protein-Protein Interactions		19 interactors: AMOTL2 ATP5C1 DNPEP ERBB2IP GADD45A GSK3B GYPC HNRNPD KLHL12 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 STK3 STUB1 TK1 ZAK	7 interactors: ADAMTSL4 AGT DGCR6 LNX1 MDFI MPP1 SAT1
Entrez ID		4354	23549
HPRD ID		02370	09924
Ensembl ID		ENSG00000130830	ENSG00000123992
Uniprot IDs		B4E325 Q00013	E7ETB3 Q9NV55 Q9ULA0
PDB IDs		2EJY 2EV8 3NEY	4DYO
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Communication Regulation Of Catalytic Activity Regulation Of Intracellular Signal Transduction Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Phosphorylation Intracellular Signal Transduction Regulation Of JNK Cascade Positive Regulation Of Cellular Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stimulus Intracellular Transport Positive Regulation Of Transferase Activity Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Fetal Process Involved In Parturition Negative Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Binding Golgi Vesicle Transport Positive Regulation Of Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway See more	Uterine Smooth Muscle Contraction Angiotensin Mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Spermidine Acetylation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Positive Regulation Of Protein Kinase C Activity Catenin Import Into Nucleus Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Angiotensin-mediated Drinking Behavior Smooth Muscle Cell Proliferation Positive Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Extracellular Matrix Constituent Secretion G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Ovarian Follicle Rupture Putrescine Catabolic Process Regulation Of Renal Output By Angiotensin Fibroblast Proliferation Astrocyte Activation Renin-angiotensin Regulation Of Aldosterone Production Oxalate Transport Regulation Of Blood Vessel Size By Renin-angiotensin Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Activation Of JAK2 Kinase Activity Establishment Of Blood-nerve Barrier MAPK Cascade Positive Regulation Of Activation Of Janus Kinase Activity Regulation Of NAD(P)H Oxidase Activity Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Artery Smooth Muscle Contraction Drinking Behavior Organ Morphogenesis Tonic Smooth Muscle Contraction Brain Renin-angiotensin System Activation Of Protein Kinase Activity Positive Regulation Of Cholesterol Esterification Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Superoxide Anion Generation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Anatomical Structure Morphogenesis Regulation Of Cholesterol Esterification Protein O-linked Fucosylation Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Transmission Of Nerve Impulse See more
Tagcloud ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	2cl abundance alternatively ascending convoluted cotransporter ctal dct fl ko ks medullary microperfusion mtal nacl ncc nkcc2 osr1 reabsorption sodium spak spliced stimulatory tal thick tubule tubules vasopressin wt
Tagcloud (Difference) ?		boundaries cdna conservation conserved construction discs drosophila encodes establish exon exons fugu gives heavily homology identity intron knockout lethal likewise location notion p55 palmitoylated puffer rubripes studying suppressor ubiquitously	2cl abundance alternatively ascending convoluted cotransporter ctal dct fl ko ks medullary microperfusion mtal nacl ncc nkcc2 osr1 reabsorption sodium spak spliced stimulatory tal thick tubule tubules vasopressin wt
Tagcloud (Intersection) ?