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RBL1 and DGKZ
Number of citations of the paper that reports this interaction (PubMedID
16286473
)
0
Data Source:
HPRD
(in vivo, in vitro)
RBL1
DGKZ
Description
RB transcriptional corepressor like 1
diacylglycerol kinase zeta
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Nuclear Speck
Lamellipodium
Cell Projection
Glutamatergic Synapse
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Protein Binding
Promoter-specific Chromatin Binding
Nucleotide Binding
Lipid Kinase Activity
ATP-dependent Diacylglycerol Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
Alkylglycerol Kinase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Gene Expression
Cell Differentiation
Regulation Of Lipid Kinase Activity
Regulation Of Cell Cycle
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Senescence
Lipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Signal Transduction
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Cell Migration
Platelet Activation
Mitotic G1 DNA Damage Checkpoint Signaling
Intracellular Signal Transduction
Diacylglycerol Metabolic Process
Glycerolipid Metabolic Process
Lipid Phosphorylation
Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
G1/S-Specific Transcription
Cyclin D associated events in G1
Effects of PIP2 hydrolysis
Drugs
alpha-Tocopherol succinate
Diseases
GWAS
Height (
25429064
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
28957414
32888494
)
Age at first sexual intercourse (
34211149
)
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Body size at age 10 (
32376654
)
Immunoglobulin A (
20694011
)
Reaction time (
29844566
)
Schizophrenia (
28991256
29483656
)
Interacting Genes
55 interacting genes:
AOX1
BEGAIN
BRCA1
BRF1
CCNA1
CCNA2
CCND1
CCNE1
CDK2
CDK4
CDK6
CEBPA
CREG1
DGKZ
DHX30
DYRK1A
E2F1
E2F4
E2F5
EPHA2
FN1
GOLGA2
HDAC1
ID2
IRF3
KDM5A
KMT5C
LAMB2
MAPK6
MCM7
MYBL2
MYC
NR2E3
NR4A1
NUCB1
PHB1
PLSCR1
PPP1R9B
PPP2R3A
RBBP8
RBBP9
RINT1
SMAD2
SMAD3
SMAD4
SMARCA4
SNRPD3
SNW1
SP1
SUV39H1
TAF1
TOP1
TP53BP1
TSC22D2
USP4
19 interacting genes:
DMD
HRAS
LEPR
MAPK6
PLCG1
POLR2M
PRKCA
RASGRP1
RB1
RBL1
RBL2
SAT1
SNTA1
SNTB1
SNTB2
SNTG1
SNX27
SRC
TP53
Entrez ID
5933
8525
HPRD ID
00312
03260
Ensembl ID
ENSG00000080839
ENSG00000149091
Uniprot IDs
P28749
Q13574
PDB IDs
1H28
4YOO
4YOS
4YOZ
5TUV
7SMC
7SMD
7SME
7SMF
5ELQ
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Transcription Regulator Complex
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Cycle
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle G1/S Phase Transition
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of RNA Metabolic Process
DNA Damage Response
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Metabolic Process
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Cycle Process
Negative Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Intracellular Signal Transduction
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Nucleus
Cellular Response To Stress
Mitotic Cell Cycle Phase Transition
Response To Stress
Cell Cycle Phase Transition
Response To Growth Factor
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Mitotic Cell Cycle
Cyclin-dependent Protein Kinase Holoenzyme Complex
DNA Binding
Dystrophin-associated Glycoprotein Complex
Syntrophin Complex
Regulation Of Lipid Kinase Activity
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle G1/S Phase Transition
Intracellular Signaling Cassette
Ras Protein Signal Transduction
Regulation Of Tissue Remodeling
Glial Cell Proliferation
Regulation Of Kinase Activity
Protein-containing Complex
Glial Cell Apoptotic Process
Regulation Of Bone Remodeling
Regulation Of Phosphorus Metabolic Process
Regulation Of Catalytic Activity
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Structural Molecule Activity
Actin Binding
Regulation Of Cell Cycle G1/S Phase Transition
Intracellular Signal Transduction
Promoter-specific Chromatin Binding
Nitric-oxide Synthase Binding
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Phosphorylation
Negative Regulation Of Cell Cycle Phase Transition
Diacylglycerol Binding
Transcription Regulator Complex
Positive Regulation Of Macrophage Differentiation
Negative Regulation Of Glial Cell Proliferation
Small GTPase-mediated Signal Transduction
Ruffle Membrane
Regulation Of Mitotic Cell Cycle
Regulation Of Heart Rate
Negative Regulation Of Cell Cycle Process
Regulation Of ERK1 And ERK2 Cascade
Neuron Apoptotic Process
Sarcolemma
Regulation Of Macrophage Differentiation
Positive Regulation Of Developmental Process
Disordered Domain Specific Binding
Cellular Response To Gamma Radiation
Regulation Of Multicellular Organismal Process
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Developmental Process
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Cell Cycle
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Immune System Process
Cytoskeleton
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Tagcloud (Intersection)
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