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DGKZ and POLR2M
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DGKZ
POLR2M
Gene Name
diacylglycerol kinase, zeta
polymerase (RNA) II (DNA directed) polypeptide M
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
Lamellipodium
Nuclear Envelope
DNA-directed RNA Polymerase II, Holoenzyme
Neuronal Cell Body
Molecular Function
Lipid Kinase Activity
NAD+ Kinase Activity
Diacylglycerol Kinase Activity
Enzyme Inhibitor Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Metal Ion Binding
DNA-directed RNA Polymerase Activity
Biological Process
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Phosphorylation
Cell Migration
Platelet Activation
Mitotic G1 DNA Damage Checkpoint
Intracellular Signal Transduction
Negative Regulation Of Catalytic Activity
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Ras Protein Signal Transduction
Lipid Phosphorylation
RNA Biosynthetic Process
Maintenance Of ER Location
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS
Immunoglobulin A (
20694011
)
Protein-Protein Interactions
18 interactors:
DMD
HRAS
LEPR
MAPK6
PLCG1
POLR2M
PRKCA
RASGRP1
RB1
RBL1
RBL2
SAT1
SNTA1
SNTB1
SNTB2
SNTG1
SNX27
SRC
19 interactors:
AHSP
ANKHD1
APOD
CEBPG
DGKZ
HIGD1B
KIAA1377
MYO3A
MYO9A
NEDD4
PSMC2
RBM4B
RPL7A
SCMH1
SIVA1
THAP1
UQCRQ
WDR89
ZNF410
Entrez ID
8525
81488
HPRD ID
03260
07575
Ensembl ID
ENSG00000149091
ENSG00000255529
Uniprot IDs
B7Z6M3
F6UCU9
Q13574
P0CAP1
P0CAP2
Q6EEV4
PDB IDs
2KXS
Enriched GO Terms of Interacting Partners
?
Regulation Of Lipid Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Phosphorylation
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Regulation Of Phosphorus Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cell Communication
Cellular Response To Fibroblast Growth Factor Stimulus
Blood Coagulation
Response To Fibroblast Growth Factor
Hemostasis
Regulation Of Catalytic Activity
Neurotrophin TRK Receptor Signaling Pathway
Ras Protein Signal Transduction
Neurotrophin Signaling Pathway
Intracellular Signal Transduction
Leukocyte Migration
Cell Cycle
Regulation Of Cell Cycle
Positive Regulation Of Macrophage Differentiation
Fc Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Cellular Response To Growth Factor Stimulus
Wound Healing
Response To Growth Factor
Regulation Of Lipid Metabolic Process
Regulation Of Cellular Localization
Signaling
Regulation Of Protein Phosphorylation
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Cellular Component Movement
Regulation Of Cellular Component Movement
Response To Wounding
Positive Regulation Of Locomotion
Positive Regulation Of ERK1 And ERK2 Cascade
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Mitotic Cell Cycle
Regulation Of Epithelial Cell Migration
Negative Regulation Of Catalytic Activity
Regulation Of Muscle Contraction
Organelle Localization
Signal Transduction
Regulation Of Immune System Process
Innate Immune Response
Viral Process
Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Negative Regulation Of T Cell Migration
Negative Regulation Of Lipoprotein Lipid Oxidation
Transmission Of Virus
Development Involved In Symbiotic Interaction
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Negative Regulation Of Smooth Muscle Cell-matrix Adhesion
Subthalamus Development
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of Lipoprotein Lipid Oxidation
Mitotic DNA Damage Checkpoint
Regulation Of Smooth Muscle Cell-matrix Adhesion
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Interaction With Host
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Lymphocyte Migration
Regulation Of Intracellular Transport
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Progesterone Receptor Signaling Pathway
Developmental Process
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