DGKZ

Gene Name		diacylglycerol kinase, zeta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Lamellipodium
	Molecular Function	Lipid Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity Enzyme Inhibitor Activity Protein Binding ATP Binding Protein C-terminus Binding Metal Ion Binding
	Biological Process	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Phosphorylation Cell Migration Platelet Activation Mitotic G1 DNA Damage Checkpoint Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Ras Protein Signal Transduction Lipid Phosphorylation
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		Immunoglobulin A ( 20694011)
Protein-protein Interactions		18 interactors: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC
Entrez ID		8525
HPRD ID		03260
Ensembl ID		ENSG00000149091
Uniprot IDs		B7Z6M3 F6UCU9 Q13574
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Lipid Kinase Activity Regulation Of Kinase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Phosphorus Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Communication Cellular Response To Fibroblast Growth Factor Stimulus Blood Coagulation Response To Fibroblast Growth Factor Hemostasis Regulation Of Catalytic Activity Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Intracellular Signal Transduction Leukocyte Migration Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Macrophage Differentiation Fc Receptor Signaling Pathway Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Wound Healing Response To Growth Factor Regulation Of Lipid Metabolic Process Regulation Of Cellular Localization Signaling Regulation Of Protein Phosphorylation Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Cellular Component Movement Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Locomotion Positive Regulation Of ERK1 And ERK2 Cascade Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Epithelial Cell Migration Negative Regulation Of Catalytic Activity Regulation Of Muscle Contraction Organelle Localization Signal Transduction Regulation Of Immune System Process Innate Immune Response
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