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DGKZ and DMD
Number of citations of the paper that reports this interaction (PMID
11352924
)
19
Data Source:
HPRD
(in vitro)
DGKZ
DMD
Gene Name
diacylglycerol kinase, zeta
dystrophin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
Lamellipodium
Nucleus
Cytosol
Cytoskeleton
Plasma Membrane
Cell Surface
Actin Cytoskeleton
Dystrophin-associated Glycoprotein Complex
Syntrophin Complex
Lateral Plasma Membrane
Cell Junction
Filopodium
Filopodium Membrane
Sarcolemma
Costamere
Protein Complex
Membrane Raft
Postsynaptic Membrane
Molecular Function
Lipid Kinase Activity
NAD+ Kinase Activity
Diacylglycerol Kinase Activity
Enzyme Inhibitor Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Metal Ion Binding
Dystroglycan Binding
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Zinc Ion Binding
Structural Constituent Of Muscle
Myosin Binding
Vinculin Binding
Nitric-oxide Synthase Binding
Biological Process
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Phosphorylation
Cell Migration
Platelet Activation
Mitotic G1 DNA Damage Checkpoint
Intracellular Signal Transduction
Negative Regulation Of Catalytic Activity
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Ras Protein Signal Transduction
Lipid Phosphorylation
Regulation Of Heart Rate
Muscle Organ Development
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Positive Regulation Of Neuron Projection Development
Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion
Regulation Of Skeletal Muscle Contraction
Muscle Filament Sliding
Extracellular Matrix Organization
Negative Regulation Of Peptidyl-serine Phosphorylation
Cellular Protein Localization
Peptide Biosynthetic Process
Cellular Protein Complex Assembly
Motile Cilium Assembly
Positive Regulation Of Neuron Differentiation
Cardiac Muscle Contraction
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Cardiac Muscle Cell Action Potential
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Voltage-gated Calcium Channel Activity
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Effects of PIP2 hydrolysis
Striated Muscle Contraction
Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Immunoglobulin A (
20694011
)
Response to antidepressant treatment (
22041458
)
Protein-Protein Interactions
18 interactors:
DMD
HRAS
LEPR
MAPK6
PLCG1
POLR2M
PRKCA
RASGRP1
RB1
RBL1
RBL2
SAT1
SNTA1
SNTB1
SNTB2
SNTG1
SNX27
SRC
27 interactors:
ACTA1
ACTC1
APP
CADPS
CADPS2
CDC25A
CTNNAL1
DAG1
DGKZ
DISC1
DTNA
DTNB
FASLG
HAUS1
KCNJ12
KRT19
KRT8
MAP3K5
PGM5
SGCZ
SNTA1
SNTB1
SNTB2
SNTG1
SNTG2
TRAF3IP1
UTRN
Entrez ID
8525
1756
HPRD ID
03260
02303
Ensembl ID
ENSG00000149091
ENSG00000198947
Uniprot IDs
B7Z6M3
F6UCU9
Q13574
A1L0U9
A7E212
P11532
Q16484
Q4G0X0
PDB IDs
1DXX
1EG3
1EG4
3UUN
Enriched GO Terms of Interacting Partners
?
Regulation Of Lipid Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Phosphorylation
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Regulation Of Phosphorus Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cell Communication
Cellular Response To Fibroblast Growth Factor Stimulus
Blood Coagulation
Response To Fibroblast Growth Factor
Hemostasis
Regulation Of Catalytic Activity
Neurotrophin TRK Receptor Signaling Pathway
Ras Protein Signal Transduction
Neurotrophin Signaling Pathway
Intracellular Signal Transduction
Leukocyte Migration
Cell Cycle
Regulation Of Cell Cycle
Positive Regulation Of Macrophage Differentiation
Fc Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Cellular Response To Growth Factor Stimulus
Wound Healing
Response To Growth Factor
Regulation Of Lipid Metabolic Process
Regulation Of Cellular Localization
Signaling
Regulation Of Protein Phosphorylation
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Cellular Component Movement
Regulation Of Cellular Component Movement
Response To Wounding
Positive Regulation Of Locomotion
Positive Regulation Of ERK1 And ERK2 Cascade
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Mitotic Cell Cycle
Regulation Of Epithelial Cell Migration
Negative Regulation Of Catalytic Activity
Regulation Of Muscle Contraction
Organelle Localization
Signal Transduction
Regulation Of Immune System Process
Innate Immune Response
Muscle Contraction
Muscle System Process
Muscle Cell Development
Myofibril Assembly
Actomyosin Structure Organization
Organelle Assembly
Cellular Component Assembly
Muscle Structure Development
Muscle Cell Differentiation
Skeletal Muscle Thin Filament Assembly
Striated Muscle Cell Development
Skeletal Myofibril Assembly
Synaptic Vesicle Priming
Striated Muscle Cell Differentiation
Organ Development
Cytoskeleton Organization
Organelle Organization
Muscle Organ Development
Positive Regulation Of Proteolysis
Cell Development
System Development
Positive Regulation Of Peptidase Activity
Cell Differentiation Involved In Embryonic Placenta Development
Actin-myosin Filament Sliding
Muscle Filament Sliding
Movement Of Cell Or Subcellular Component
Regulation Of Sodium Ion Transmembrane Transport
Microtubule-based Process
Actin-mediated Cell Contraction
Programmed Necrotic Cell Death
Nerve Maturation
Regulation Of Vasoconstriction By Circulating Norepinephrine
Necrotic Cell Death
Multicellular Organismal Development
Sarcomere Organization
Neuromuscular Junction Development
Synaptic Vesicle Exocytosis
Anatomical Structure Development
Actin Filament-based Movement
Cell-cell Signaling
Heart Contraction
Skeletal Muscle Fiber Adaptation
Synaptic Growth At Neuromuscular Junction
Calcium-dependent Cell-matrix Adhesion
Regulation Of Sodium Ion Transport
Anatomical Structure Morphogenesis
Viral Process
Apoptotic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Tagcloud
?
2gamma
chromosome
dffry
encode
escape
escapes
eutherian
homologue
homologues
identity
inactivation
kangaroo
maps
metatherian
primates
retroposon
retroposons
shed
simian
smcy
spermatogenesis
sxrb
ube1y
ubiquitously
uty
xp21
y
zfy1
zfy2
Tagcloud (Difference)
?
2gamma
chromosome
dffry
encode
escape
escapes
eutherian
homologue
homologues
identity
inactivation
kangaroo
maps
metatherian
primates
retroposon
retroposons
shed
simian
smcy
spermatogenesis
sxrb
ube1y
ubiquitously
uty
xp21
y
zfy1
zfy2
Tagcloud (Intersection)
?