RBL1 and RBBP9

Number of citations of the paper that reports this interaction (PubMedID 9697699)
0

Data Source:
HPRD (in vivo)

		RBL1	RBBP9
Description		RB transcriptional corepressor like 1	RB binding protein 9, serine hydrolase
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Promoter-specific Chromatin Binding	Protein Binding Hydrolase Activity Serine Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Cell Differentiation Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Senescence	Xenobiotic Metabolic Process Response To Nematode Positive Regulation Of Gene Expression Type II Pneumocyte Differentiation
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest G1/S-Specific Transcription Cyclin D associated events in G1
Drugs
Diseases
GWAS		Height ( 25429064) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 28957414 32888494)
Interacting Genes		55 interacting genes: AOX1 BEGAIN BRCA1 BRF1 CCNA1 CCNA2 CCND1 CCNE1 CDK2 CDK4 CDK6 CEBPA CREG1 DGKZ DHX30 DYRK1A E2F1 E2F4 E2F5 EPHA2 FN1 GOLGA2 HDAC1 ID2 IRF3 KDM5A KMT5C LAMB2 MAPK6 MCM7 MYBL2 MYC NR2E3 NR4A1 NUCB1 PHB1 PLSCR1 PPP1R9B PPP2R3A RBBP8 RBBP9 RINT1 SMAD2 SMAD3 SMAD4 SMARCA4 SNRPD3 SNW1 SP1 SUV39H1 TAF1 TOP1 TP53BP1 TSC22D2 USP4	6 interacting genes: RB1 RBL1 RBL2 RCBTB2 TERF2IP YRDC
Entrez ID		5933	10741
HPRD ID		00312	04217
Ensembl ID		ENSG00000080839	ENSG00000089050
Uniprot IDs		P28749	O75884
PDB IDs		1H28 4YOO 4YOS 4YOZ 5TUV 7SMC 7SMD 7SME 7SMF	2QS9 7OEX 9FCR
Enriched GO Terms of Interacting Partners?		Nucleoplasm Transcription Regulator Complex Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process DNA Damage Response Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Intracellular Signal Transduction Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nucleus Cellular Response To Stress Mitotic Cell Cycle Phase Transition Response To Stress Cell Cycle Phase Transition Response To Growth Factor Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex DNA Binding	Regulation Of Lipid Kinase Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Transcription Regulator Complex Regulation Of Kinase Activity Negative Regulation Of Cell Cycle Process Digestive Tract Development Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Promoter-specific Chromatin Binding Regulation Of Cell Cycle Phase Transition L-threonylcarbamoyladenylate Synthase Regulation Of Mitotic Cell Cycle Protein Localization To Chromosome Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Negative Regulation Of Phosphorylation Negative Regulation Of DNA Recombination At Telomere Chromatin Lock Complex Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Negative Regulation Of Phosphate Metabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Collagen Fibril Organization Glial Cell Apoptotic Process Rb-E2F Complex TRNA Threonylcarbamoyladenosine Modification Negative Regulation Of Myofibroblast Differentiation Chromatin Organization Negative Regulation Of Hepatocyte Apoptotic Process Regulation Of Centromere Complex Assembly Shelterin Complex Tube Development Enucleate Erythrocyte Differentiation Protection From Non-homologous End Joining At Telomere Cyclin/CDK Positive Transcription Elongation Factor Complex Regulation Of Chromosome Organization Regulation Of Myofibroblast Differentiation Regulation Of Collagen Fibril Organization Importin-alpha Family Protein Binding Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding
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