RRAS2 and AHSG

Number of citations of the paper that reports this interaction (PMID 11788587)
15

Data Source:
HPRD (in vitro)

		RRAS2	AHSG
Gene Name		related RAS viral (r-ras) oncogene homolog 2	alpha-2-HS-glycoprotein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Focal Adhesion Membrane Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Cysteine-type Endopeptidase Inhibitor Activity Kinase Inhibitor Activity
	Biological Process	Osteoblast Differentiation Ras Protein Signal Transduction Positive Regulation Of Cell Migration Regulation Of Neuron Death	Skeletal System Development Ossification Pinocytosis Acute-phase Response Negative Regulation Of Endopeptidase Activity Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Negative Regulation Of Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)	Activated partial thromboplastin time ( 22703881)
Protein-Protein Interactions		29 interactors: ACVR1 AHSG ARAF ARHGEF2 BMPR1B CREB3 FNTB LGALS4 MLLT4 PAWR PGGT1B PIK3R1 PTPN1 RABAC1 RAF1 RALGDS RAPGEF1 RAPGEF3 RAPGEF4 RASGRF1 RASIP1 RASSF5 RIN1 SMAD3 SMAD4 SMURF2 TRAF2 TRAF3 XRCC6	7 interactors: CDC42 DCN FBXO2 GRB2 INSR RRAS2 VKORC1
Entrez ID		22800	197
HPRD ID		02518	00727
Ensembl ID		ENSG00000133818	ENSG00000145192
Uniprot IDs		B7Z5Z2 P62070	P02765
PDB IDs		2ERY
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Metabolic Process Signal Transduction Response To Stimulus Signaling Cell Communication Positive Regulation Of Metabolic Process Cellular Response To Stimulus Intracellular Signal Transduction Regulation Of Phosphorylation Regulation Of Catalytic Activity Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Hydrolase Activity Cellular Response To Growth Factor Stimulus Regulation Of Protein Phosphorylation Response To Growth Factor Regulation Of Intracellular Signal Transduction Endothelial Cell Differentiation Positive Regulation Of Catalytic Activity Regulation Of Cell Death Endothelium Development Regulation Of Cellular Protein Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cellular Process Regulation Of GTPase Activity Response To Stress Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Cell Surface Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Signaling Regulation Of Ras Protein Signal Transduction Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Rap GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Bone Mineralization Defense Response BMP Signaling Pathway Regulation Of Cytokine Production Regulation Of Ras GTPase Activity Regulation Of Protein Localization	Wound Healing Response To Wounding Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Exocrine System Development Positive Regulation Of DNA Replication Blood Coagulation Hemostasis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway T Cell Costimulation Regulation Of ERBB Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Body Fluid Levels Organ Development Regulation Of Mitotic Nuclear Division Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of DNA Replication Positive Regulation Of Cell Division Protein Heterooligomerization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of DNA Metabolic Process Tissue Development Insulin Receptor Signaling Pathway Actin Filament Branching Transformation Of Host Cell By Virus Submandibular Salivary Gland Formation Developmental Process Regulation Of Reactive Oxygen Species Metabolic Process Developmental Process Involved In Reproduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Intracellular Signal Transduction Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Placenta Development Positive Regulation Of T Cell Activation Cellular Response To Insulin Stimulus Establishment Of Golgi Localization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Regulation Of Organelle Organization Positive Regulation Of Cell Cycle Process Leukocyte Migration Vitamin K Metabolic Process
Tagcloud ?			actual african americans associations caucasian caucasians causal diabetes directions fasting fetuin genetically glucose incident insignificant mendelian null predicted prevalent proxies raising randomization rs2248690 rs4917 sd snps trended unbiased variants
Tagcloud (Difference) ?			actual african americans associations caucasian caucasians causal diabetes directions fasting fetuin genetically glucose incident insignificant mendelian null predicted prevalent proxies raising randomization rs2248690 rs4917 sd snps trended unbiased variants
Tagcloud (Intersection) ?