PTPN12 and PRKCA

  • Number of citations of the paper that reports this interaction (PMID 7520867)
  • 24
  • Data Source:
  • HPRD (in vitro)

PTPN12

PRKCA

Gene Name protein tyrosine phosphatase, non-receptor type 12 protein kinase C, alpha
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Height ( 22021425)
  • Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
  • Ventricular conduction ( 21076409)
Protein-Protein Interactions 37 interactors: ABL1 APP BAG6 BCAR1 CGA CSH1 CSH2 CSK EFS EGFR FLT3 GRB2 IFT20 INSR JAK2 LPXN MYCBP2 NEDD9 PRKACA PRKCA PSG9 PSTPIP1 PSTPIP2 PTK2 PTK2B PXN RBM19 SHC1 SMAD5 SORBS2 STX16 TEX10 TGFB1I1 THAP2 UTRN WAS ZFP2 210 interactors: ACTA1 ADAP1 ADCY5 ADD3 ADRA1B ADRBK1 AFAP1 AKAP12 AKAP5 ANXA2 ANXA7 APLP2 ARHGEF1 ATP1A1 ATP2B1 ATP2B2 AVPR1A BCL2 BTG2 BTK C1QBP CASR CBL CD163 CD5 CD9 CDC42 CDKN2A CFTR CHAT CISH CORO1B CREM CYP3A4 CYTH2 DDX5 DGKD DGKZ DLG4 DLX3 DNM1 DVL2 EDF1 EEF1D EGFR EIF4E EIF4EBP1 ELAVL1 ENTPD5 EP300 EWSR1 EZR F11R FAS FBXO25 FLNA FLNC FSCN1 GABRB3 GABRG2 GABRR1 GABRR2 GFAP GFPT1 GJA1 GJB1 GLI3 GMFB GNA12 GNA15 GNB2L1 GPM6A GRIA1 GRIA2 GRIA4 GRIN1 GRIN2A GRIN2B GRM1 GRM5 GSK3A GSK3B HABP4 HAND1 HAND2 HES1 HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HIST1H1T HIST1H3A HIST3H3 HLA-A HMGA1 HMGA2 HMGB1 HMGN1 HMGN2 HSP90AA1 HSPA1A HSPB8 IKBKB INSR ITGB1 ITGB2 ITGB4 ITPKA ITPKB KCNE1 KCNE4 KCNQ2 KIT KLF5 KRT18 LCK LMNA LMNB1 MARCKS MBP MGMT MTOR MYLK MYOD1 NCF1 NFATC1 NFE2L2 NFKBIA NOS1 NR1H2 NRGN NUMB OGG1 OPRD1 PA2G4 PAM PDLIM7 PEA15 PEBP1 PFKFB1 PFKFB2 PICK1 PLCB1 PLD1 PLD2 POLB PPARA PPARG PPP1R14A PRKCZ PRKG1 PSMB4 PTGIR PTPN11 PTPN12 PTPN6 RAC1 RAF1 RALBP1 RARA RBCK1 RGS19 RGS2 RGS7 RHO RHOA RNF31 RPL10 RRAD SACM1L SCRIB SCTR SDC2 SDC4 SDPR SELL SEMG1 SEMG2 SHC1 SLC1A1 SLC6A9 SNAP23 SNAP25 SPAG1 SPP1 SRC STXBP1 STXBP3 SYK TBXA2R TEP1 TERT THOC5 TIAM1 TNNI3 TNNT2 TNP1 TNP2 TOP2A TP53 TRIM29 TRIM41 TRPC3 TRPV6 VCL VTN XK YWHAG YWHAZ
Entrez ID 5782 5578
HPRD ID 02513 01498
Ensembl ID ENSG00000127947 ENSG00000154229
Uniprot IDs A4D1C5 B4E105 E9PBR5 Q05209 P17252 Q7Z727
PDB IDs 2ELI 3IW4 4DNL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  inpp5d  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
Tagcloud (Difference) ?
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  inpp5d  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
Tagcloud (Intersection) ?