PTPN12

Gene Name		protein tyrosine phosphatase, non-receptor type 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Cytoplasm Cytosol Plasma Membrane Cell Junction Cell Projection
	Molecular Function	Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding SH3 Domain Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		37 interactors: ABL1 APP BAG6 BCAR1 CGA CSH1 CSH2 CSK EFS EGFR FLT3 GRB2 IFT20 INSR JAK2 LPXN MYCBP2 NEDD9 PRKACA PRKCA PSG9 PSTPIP1 PSTPIP2 PTK2 PTK2B PXN RBM19 SHC1 SMAD5 SORBS2 STX16 TEX10 TGFB1I1 THAP2 UTRN WAS ZFP2
Entrez ID		5782
HPRD ID		02513
Ensembl ID		ENSG00000127947
Uniprot IDs		A4D1C5 B4E105 E9PBR5 Q05209
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Adhesion Protein Autophosphorylation Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Movement Of Cell Or Subcellular Component Response To Organonitrogen Compound Cell Activation Regulation Of Protein Kinase Activity Blood Coagulation Peptidyl-tyrosine Autophosphorylation Hemostasis Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Positive Regulation Of MAPK Cascade Cellular Response To Peptide Signal Transduction Regulation Of Kinase Activity Regulation Of MAPK Cascade Innate Immune Response Cell Surface Receptor Signaling Pathway Signaling Positive Regulation Of Protein Phosphorylation Cell Communication Regulation Of MAP Kinase Activity Peptidyl-amino Acid Modification Response To Hormone Cellular Response To Growth Factor Stimulus Platelet Activation Regulation Of Body Fluid Levels Response To Growth Factor Wound Healing Locomotion Response To Peptide Hormone Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cell Migration Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Kinase Activity Protein Phosphorylation Immune System Process Regulation Of Immune System Process Regulation Of Phosphorylation Response To Peptide
Tagcloud ?		cytoskeleton dataset deposited dysregulation exerts expand heterodimeric http identifier inositol inpp5d mapkapk2 nad nadk nonreceptor org pertaining phosphatases phosphoproteome phosphoproteomic polyphosphate proteomecentral proteomexchange pxd000984 reorganization ripk1 silac threonine tnfrsf