PTPRZ1 and GIT1

Number of citations of the paper that reports this interaction (PMID 11381105)
18

Data Source:
HPRD (two hybrid, in vivo)

		PTPRZ1	GIT1
Gene Name		protein tyrosine phosphatase, receptor-type, Z polypeptide 1	G protein-coupled receptor kinase interacting ArfGAP 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Integral Component Of Plasma Membrane Perineuronal Net	Cytoplasm Cytosol Focal Adhesion Membrane Aggresome
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Peptidyl-tyrosine Dephosphorylation Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation	Axon Guidance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway
Pathways			Ephrin signaling Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 MDK PTN TNR	50 interactors: ADRBK1 ADRBK2 ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CENPU CHD3 DDX24 EIF6 GIT2 GRB2 GRK5 GRK6 HAP1 HMOX2 HTT KIAA1377 KIF1A LAMTOR5 LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SDCCAG3 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG
Entrez ID		5803	28964
HPRD ID		01481	06577
Ensembl ID		ENSG00000106278	ENSG00000108262
Uniprot IDs		B4DFE7 C9JFM0 P23471	Q59FC3 Q9Y2X7
PDB IDs		3JXF 3S97
Enriched GO Terms of Interacting Partners?		Nervous System Development System Development Neuron Differentiation Multicellular Organismal Development Locomotion Anatomical Structure Development Movement Of Cell Or Subcellular Component Forebrain Development Developmental Process Generation Of Neurons Neuron Development Neurogenesis Cell Development Chemotaxis Learning Or Memory Cognition Cell Morphogenesis Involved In Differentiation Cell Differentiation Brain Development Head Development Neuron Projection Development Cell Migration Axon Guidance Cell Motility Learning Central Nervous System Development Single-organism Behavior Regulation Of Cell Morphogenesis Response To External Stimulus Cell Morphogenesis Regulation Of DNA-templated Transcription, Initiation Organ Development Regulation Of Cellular Component Organization Axonogenesis Cell Projection Organization Axon Development Negative Regulation Of Neuron Death Cell Morphogenesis Involved In Neuron Differentiation Behavior Neuron Projection Morphogenesis Regulation Of Neurogenesis Regulation Of Cell Division Regulation Of Apoptotic Process Regulation Of Neuron Death Telencephalon Development Regulation Of Cell Death Cell Projection Morphogenesis Regulation Of Cell Development Cell Part Morphogenesis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Termination Of Signal Transduction Glutamate Secretion Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Signal Complex Assembly Regulation Of Neurotransmitter Levels Cellular Response To Organic Substance Immune Response-regulating Cell Surface Receptor Signaling Pathway Dicarboxylic Acid Transport Fibroblast Growth Factor Receptor Signaling Pathway Neurotransmitter Transport Fc Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Protein Kinase Activity Cell Projection Organization Regulation Of Catalytic Activity Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotransmitter Secretion Regulation Of Kinase Activity Response To Peptide Hormone Immune Response-regulating Signaling Pathway Positive Regulation Of Metabolic Process Cell-substrate Adhesion Regulation Of Apoptotic Process Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Response To Peptide Positive Regulation Of Signal Transduction Signaling Acid Secretion Negative Regulation Of Signal Transduction Regulation Of Phosphorylation
Tagcloud ?		alters annotation ca3 candidate cdh23 dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1	ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		alters annotation ca3 candidate cdh23 dataset disequilibrium ear fdr filtering gwas harbored hist3h3 hypotheses hypothetical icsnpathway il27ra innate modulates morphogenesis pneumoconiosis rs11592462 rs2230656 rs2292151 rs8120 snps stereocilia strongest ticam1	ancient autophosphorylation coordinates deregulated dimerization exchange gef git2 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?